Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels

Light has limited penetration depth in vivo which has led to increasing interest in NIR-II fluorophores. Here, the authors report on the design and testing of an organic aggregation induced emission fluorophore with high quantum yield and demonstrate imaging of vasculature and intestines in live mic...

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Autores principales: Yuanyuan Li, Zhaochong Cai, Shunjie Liu, Haoke Zhang, Sherman T. H. Wong, Jacky W. Y. Lam, Ryan T. K. Kwok, Jun Qian, Ben Zhong Tang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/5e74f70a086a4b2683a3e91ea5282591
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spelling oai:doaj.org-article:5e74f70a086a4b2683a3e91ea52825912021-12-02T17:33:14ZDesign of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels10.1038/s41467-020-15095-12041-1723https://doaj.org/article/5e74f70a086a4b2683a3e91ea52825912020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15095-1https://doaj.org/toc/2041-1723Light has limited penetration depth in vivo which has led to increasing interest in NIR-II fluorophores. Here, the authors report on the design and testing of an organic aggregation induced emission fluorophore with high quantum yield and demonstrate imaging of vasculature and intestines in live mice.Yuanyuan LiZhaochong CaiShunjie LiuHaoke ZhangSherman T. H. WongJacky W. Y. LamRyan T. K. KwokJun QianBen Zhong TangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yuanyuan Li
Zhaochong Cai
Shunjie Liu
Haoke Zhang
Sherman T. H. Wong
Jacky W. Y. Lam
Ryan T. K. Kwok
Jun Qian
Ben Zhong Tang
Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels
description Light has limited penetration depth in vivo which has led to increasing interest in NIR-II fluorophores. Here, the authors report on the design and testing of an organic aggregation induced emission fluorophore with high quantum yield and demonstrate imaging of vasculature and intestines in live mice.
format article
author Yuanyuan Li
Zhaochong Cai
Shunjie Liu
Haoke Zhang
Sherman T. H. Wong
Jacky W. Y. Lam
Ryan T. K. Kwok
Jun Qian
Ben Zhong Tang
author_facet Yuanyuan Li
Zhaochong Cai
Shunjie Liu
Haoke Zhang
Sherman T. H. Wong
Jacky W. Y. Lam
Ryan T. K. Kwok
Jun Qian
Ben Zhong Tang
author_sort Yuanyuan Li
title Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels
title_short Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels
title_full Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels
title_fullStr Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels
title_full_unstemmed Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels
title_sort design of aiegens for near-infrared iib imaging through structural modulation at molecular and morphological levels
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/5e74f70a086a4b2683a3e91ea5282591
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