Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels
Light has limited penetration depth in vivo which has led to increasing interest in NIR-II fluorophores. Here, the authors report on the design and testing of an organic aggregation induced emission fluorophore with high quantum yield and demonstrate imaging of vasculature and intestines in live mic...
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Nature Portfolio
2020
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oai:doaj.org-article:5e74f70a086a4b2683a3e91ea52825912021-12-02T17:33:14ZDesign of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels10.1038/s41467-020-15095-12041-1723https://doaj.org/article/5e74f70a086a4b2683a3e91ea52825912020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15095-1https://doaj.org/toc/2041-1723Light has limited penetration depth in vivo which has led to increasing interest in NIR-II fluorophores. Here, the authors report on the design and testing of an organic aggregation induced emission fluorophore with high quantum yield and demonstrate imaging of vasculature and intestines in live mice.Yuanyuan LiZhaochong CaiShunjie LiuHaoke ZhangSherman T. H. WongJacky W. Y. LamRyan T. K. KwokJun QianBen Zhong TangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
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Science Q |
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Science Q Yuanyuan Li Zhaochong Cai Shunjie Liu Haoke Zhang Sherman T. H. Wong Jacky W. Y. Lam Ryan T. K. Kwok Jun Qian Ben Zhong Tang Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels |
description |
Light has limited penetration depth in vivo which has led to increasing interest in NIR-II fluorophores. Here, the authors report on the design and testing of an organic aggregation induced emission fluorophore with high quantum yield and demonstrate imaging of vasculature and intestines in live mice. |
format |
article |
author |
Yuanyuan Li Zhaochong Cai Shunjie Liu Haoke Zhang Sherman T. H. Wong Jacky W. Y. Lam Ryan T. K. Kwok Jun Qian Ben Zhong Tang |
author_facet |
Yuanyuan Li Zhaochong Cai Shunjie Liu Haoke Zhang Sherman T. H. Wong Jacky W. Y. Lam Ryan T. K. Kwok Jun Qian Ben Zhong Tang |
author_sort |
Yuanyuan Li |
title |
Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels |
title_short |
Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels |
title_full |
Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels |
title_fullStr |
Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels |
title_full_unstemmed |
Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels |
title_sort |
design of aiegens for near-infrared iib imaging through structural modulation at molecular and morphological levels |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/5e74f70a086a4b2683a3e91ea5282591 |
work_keys_str_mv |
AT yuanyuanli designofaiegensfornearinfrarediibimagingthroughstructuralmodulationatmolecularandmorphologicallevels AT zhaochongcai designofaiegensfornearinfrarediibimagingthroughstructuralmodulationatmolecularandmorphologicallevels AT shunjieliu designofaiegensfornearinfrarediibimagingthroughstructuralmodulationatmolecularandmorphologicallevels AT haokezhang designofaiegensfornearinfrarediibimagingthroughstructuralmodulationatmolecularandmorphologicallevels AT shermanthwong designofaiegensfornearinfrarediibimagingthroughstructuralmodulationatmolecularandmorphologicallevels AT jackywylam designofaiegensfornearinfrarediibimagingthroughstructuralmodulationatmolecularandmorphologicallevels AT ryantkkwok designofaiegensfornearinfrarediibimagingthroughstructuralmodulationatmolecularandmorphologicallevels AT junqian designofaiegensfornearinfrarediibimagingthroughstructuralmodulationatmolecularandmorphologicallevels AT benzhongtang designofaiegensfornearinfrarediibimagingthroughstructuralmodulationatmolecularandmorphologicallevels |
_version_ |
1718380002157789184 |