Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1
Abstract Formyl peptide receptor 1 (FPR1) mediates bacterial and mitochondrial N-formyl peptides-induced neutrophil activation. Therefore, FPR1 is an important therapeutic target for drugs to treat septic or sterile inflammatory diseases. Honokiol, a major bioactive compound of Magnoliaceae plants,...
Enregistré dans:
Auteurs principaux: | Fu-Chao Liu, Huang-Ping Yu, Yu-Ting Syu, Jia-You Fang, Chwan-Fwu Lin, Shih-Hsin Chang, Yen-Tung Lee, Tsong-Long Hwang |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/5e76b5a87cc04a5e801e9ff57c6aee21 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Structural basis of ligand binding modes at the human formyl peptide receptor 2
par: Tong Chen, et autres
Publié: (2020) -
Real-time detection of implant-associated neutrophil responses using a formyl peptide receptor-targeting NIR nanoprobe
par: Zhou J, et autres
Publié: (2012) -
The Expression of Formyl Peptide Receptor 1 is Correlated with Tumor Invasion of Human Colorectal Cancer
par: Shu-Qin Li, et autres
Publié: (2017) -
Pyridinone Derivatives as Interesting Formyl Peptide Receptor (FPR) Agonists for the Treatment of Rheumatoid Arthritis
par: Letizia Crocetti, et autres
Publié: (2021) -
Rhodaelectro-catalyzed access to chromones via formyl C–H activation towards peptide electro-labeling
par: Maximilian Stangier, et autres
Publié: (2021)