Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1
Abstract Formyl peptide receptor 1 (FPR1) mediates bacterial and mitochondrial N-formyl peptides-induced neutrophil activation. Therefore, FPR1 is an important therapeutic target for drugs to treat septic or sterile inflammatory diseases. Honokiol, a major bioactive compound of Magnoliaceae plants,...
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Auteurs principaux: | , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/5e76b5a87cc04a5e801e9ff57c6aee21 |
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