Identification of new target proteins of a Urotensin-II receptor antagonist using transcriptome-based drug repositioning approach

Abstract Drug repositioning research using transcriptome data has recently attracted attention. In this study, we attempted to identify new target proteins of the urotensin-II receptor antagonist, KR-37524 (4-(3-bromo-4-(piperidin-4-yloxy)benzyl)-N-(3-(dimethylamino)phenyl)piperazine-1-carboxamide d...

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Autores principales: Gyutae Lim, Chae Jo Lim, Jeong Hyun Lee, Byung Ho Lee, Jae Yong Ryu, Kwang-Seok Oh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5e79377f13c34e84b8825e436aafd9b7
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