Drug-Related Problems and Their Predictors Among Patients with Diabetes Attending the Ambulatory Clinic of Gebre Tsadik Shawo General Hospital, Southwest Ethiopia

Desalegn Feyissa Mechessa, Bezie Kebede Department of Pharmacy, College of Medicine and Health Science, Mizan-Tepi University, Mizan-Aman, EthiopiaCorrespondence: Desalegn Feyissa Mechessa Tel +251917127556Email sinaawayya@gmail.comBackground: Patients with diabetes are vulnerable to experiencing dr...

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Autores principales:	Mechessa DF, Kebede B
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	drug related problem diabetes ethiopia Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/5e83bba084464e03b13fd3c14c2f077d
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spelling	oai:doaj.org-article:5e83bba084464e03b13fd3c14c2f077d2021-12-02T05:30:01ZDrug-Related Problems and Their Predictors Among Patients with Diabetes Attending the Ambulatory Clinic of Gebre Tsadik Shawo General Hospital, Southwest Ethiopia1178-7007https://doaj.org/article/5e83bba084464e03b13fd3c14c2f077d2020-09-01T00:00:00Zhttps://www.dovepress.com/drug-related-problems-and-their-predictors-among-patients-with-diabete-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Desalegn Feyissa Mechessa, Bezie Kebede Department of Pharmacy, College of Medicine and Health Science, Mizan-Tepi University, Mizan-Aman, EthiopiaCorrespondence: Desalegn Feyissa Mechessa Tel +251917127556Email sinaawayya@gmail.comBackground: Patients with diabetes are vulnerable to experiencing drug-related problems. Thus, this study aimed to assess drug-related problems and their predictors among patients with diabetes attending the ambulatory clinic of Gebre Tsadik Shawo General Hospital.Methods: A cross-sectional study was conducted from September 1, 2019 to November 30, 2019. Drug-related problems were identified using the Pharmaceutical Care Network Europe version 5.01. Patient’s written informed consent was obtained after explaining the purpose of the study. The data were collected using structured questionnaires and entered into Epi data version 4.0.2. Then, it was exported to SPSS version 21.0 for analysis. To identify predictors of the occurrence of drug-related problems, multiple stepwise backward logistic regression analysis was done. For the accuracy of data analysis, a 95% confidence interval was used, and statistical significance was considered at p-values < 0.05.Results: From a total of 141 patients with diabetes included in the study, 58.2% of them had at least one drug-related problem during the 3-month study period. A total of 156 drug-related problems were identified in 141 patients. Drug interactions (30.76%) and drug choice problems (25%) were the most common type of drug-related problems identified. Presence of disease comorbidity (AOR=4.12, 95% CI=1.71– 9.91), poly-pharmacy (AOR=6.27, 95% CI=1.67– 23.52) and more than 5 years diabetes duration (AOR=3.89, 95% CI=1.52– 9.95) were independent predictors of drug-related problems.Conclusion: Drug-related problems were high among patients with diabetes in the study setting. Early detection of drug-related problems ensures the appropriateness of drug therapy. Therefore, a sustainable pharmaceutical care service is needed for early identification, prevention and resolution of drug-related problems.Keywords: drug-related problems, diabetes, EthiopiaMechessa DFKebede BDove Medical Pressarticledrug related problemdiabetesethiopiaSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 13, Pp 3349-3357 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	drug related problem diabetes ethiopia Specialties of internal medicine RC581-951
spellingShingle	drug related problem diabetes ethiopia Specialties of internal medicine RC581-951 Mechessa DF Kebede B Drug-Related Problems and Their Predictors Among Patients with Diabetes Attending the Ambulatory Clinic of Gebre Tsadik Shawo General Hospital, Southwest Ethiopia
description	Desalegn Feyissa Mechessa, Bezie Kebede Department of Pharmacy, College of Medicine and Health Science, Mizan-Tepi University, Mizan-Aman, EthiopiaCorrespondence: Desalegn Feyissa Mechessa Tel +251917127556Email sinaawayya@gmail.comBackground: Patients with diabetes are vulnerable to experiencing drug-related problems. Thus, this study aimed to assess drug-related problems and their predictors among patients with diabetes attending the ambulatory clinic of Gebre Tsadik Shawo General Hospital.Methods: A cross-sectional study was conducted from September 1, 2019 to November 30, 2019. Drug-related problems were identified using the Pharmaceutical Care Network Europe version 5.01. Patient’s written informed consent was obtained after explaining the purpose of the study. The data were collected using structured questionnaires and entered into Epi data version 4.0.2. Then, it was exported to SPSS version 21.0 for analysis. To identify predictors of the occurrence of drug-related problems, multiple stepwise backward logistic regression analysis was done. For the accuracy of data analysis, a 95% confidence interval was used, and statistical significance was considered at p-values < 0.05.Results: From a total of 141 patients with diabetes included in the study, 58.2% of them had at least one drug-related problem during the 3-month study period. A total of 156 drug-related problems were identified in 141 patients. Drug interactions (30.76%) and drug choice problems (25%) were the most common type of drug-related problems identified. Presence of disease comorbidity (AOR=4.12, 95% CI=1.71– 9.91), poly-pharmacy (AOR=6.27, 95% CI=1.67– 23.52) and more than 5 years diabetes duration (AOR=3.89, 95% CI=1.52– 9.95) were independent predictors of drug-related problems.Conclusion: Drug-related problems were high among patients with diabetes in the study setting. Early detection of drug-related problems ensures the appropriateness of drug therapy. Therefore, a sustainable pharmaceutical care service is needed for early identification, prevention and resolution of drug-related problems.Keywords: drug-related problems, diabetes, Ethiopia
format	article
author	Mechessa DF Kebede B
author_facet	Mechessa DF Kebede B
author_sort	Mechessa DF
title	Drug-Related Problems and Their Predictors Among Patients with Diabetes Attending the Ambulatory Clinic of Gebre Tsadik Shawo General Hospital, Southwest Ethiopia
title_short	Drug-Related Problems and Their Predictors Among Patients with Diabetes Attending the Ambulatory Clinic of Gebre Tsadik Shawo General Hospital, Southwest Ethiopia
title_full	Drug-Related Problems and Their Predictors Among Patients with Diabetes Attending the Ambulatory Clinic of Gebre Tsadik Shawo General Hospital, Southwest Ethiopia
title_fullStr	Drug-Related Problems and Their Predictors Among Patients with Diabetes Attending the Ambulatory Clinic of Gebre Tsadik Shawo General Hospital, Southwest Ethiopia
title_full_unstemmed	Drug-Related Problems and Their Predictors Among Patients with Diabetes Attending the Ambulatory Clinic of Gebre Tsadik Shawo General Hospital, Southwest Ethiopia
title_sort	drug-related problems and their predictors among patients with diabetes attending the ambulatory clinic of gebre tsadik shawo general hospital, southwest ethiopia
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/5e83bba084464e03b13fd3c14c2f077d
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Drug-Related Problems and Their Predictors Among Patients with Diabetes Attending the Ambulatory Clinic of Gebre Tsadik Shawo General Hospital, Southwest Ethiopia

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