Neuropeptide Y (NPY) intranasal delivery alleviates Machado–Joseph disease

Abstract Machado–Joseph disease (MJD) is the most common dominantly-inherited ataxia worldwide with no effective treatment to prevent, stop or alleviate its progression. Neuropeptide Y (NPY) is a neuroprotective agent widely expressed in the mammalian brain. Our previous work showed that NPY overexp...

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Bibliographic Details
Main Authors: Joana Duarte-Neves, Cláudia Cavadas, Luís Pereira de Almeida
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/5e8895de18654bcbb26bcfb30a822f35
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