Auditory stimuli mimicking ambient sounds drive temporal "delta-brushes" in premature infants.

In the premature infant, somatosensory and visual stimuli trigger an immature electroencephalographic (EEG) pattern, "delta-brushes," in the corresponding sensory cortical areas. Whether auditory stimuli evoke delta-brushes in the premature auditory cortex has not been reported. Here, resp...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mathilde Chipaux, Matthew T Colonnese, Audrey Mauguen, Laure Fellous, Mostafa Mokhtari, Oscar Lezcano, Mathieu Milh, Olivier Dulac, Catherine Chiron, Rustem Khazipov, Anna Kaminska
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5e8a07e153414a61a2b48f79962abe03
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5e8a07e153414a61a2b48f79962abe03
record_format	dspace
spelling	oai:doaj.org-article:5e8a07e153414a61a2b48f79962abe032021-11-18T08:47:28ZAuditory stimuli mimicking ambient sounds drive temporal "delta-brushes" in premature infants.1932-620310.1371/journal.pone.0079028https://doaj.org/article/5e8a07e153414a61a2b48f79962abe032013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24244408/?tool=EBIhttps://doaj.org/toc/1932-6203In the premature infant, somatosensory and visual stimuli trigger an immature electroencephalographic (EEG) pattern, "delta-brushes," in the corresponding sensory cortical areas. Whether auditory stimuli evoke delta-brushes in the premature auditory cortex has not been reported. Here, responses to auditory stimuli were studied in 46 premature infants without neurologic risk aged 31 to 38 postmenstrual weeks (PMW) during routine EEG recording. Stimuli consisted of either low-volume technogenic "clicks" near the background noise level of the neonatal care unit, or a human voice at conversational sound level. Stimuli were administrated pseudo-randomly during quiet and active sleep. In another protocol, the cortical response to a composite stimulus ("click" and voice) was manually triggered during EEG hypoactive periods of quiet sleep. Cortical responses were analyzed by event detection, power frequency analysis and stimulus locked averaging. Before 34 PMW, both voice and "click" stimuli evoked cortical responses with similar frequency-power topographic characteristics, namely a temporal negative slow-wave and rapid oscillations similar to spontaneous delta-brushes. Responses to composite stimuli also showed a maximal frequency-power increase in temporal areas before 35 PMW. From 34 PMW the topography of responses in quiet sleep was different for "click" and voice stimuli: responses to "clicks" became diffuse but responses to voice remained limited to temporal areas. After the age of 35 PMW auditory evoked delta-brushes progressively disappeared and were replaced by a low amplitude response in the same location. Our data show that auditory stimuli mimicking ambient sounds efficiently evoke delta-brushes in temporal areas in the premature infant before 35 PMW. Along with findings in other sensory modalities (visual and somatosensory), these findings suggest that sensory driven delta-brushes represent a ubiquitous feature of the human sensory cortex during fetal stages and provide a potential test of functional cortical maturation during fetal development.Mathilde ChipauxMatthew T ColonneseAudrey MauguenLaure FellousMostafa MokhtariOscar LezcanoMathieu MilhOlivier DulacCatherine ChironRustem KhazipovAnna KaminskaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 11, p e79028 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mathilde Chipaux Matthew T Colonnese Audrey Mauguen Laure Fellous Mostafa Mokhtari Oscar Lezcano Mathieu Milh Olivier Dulac Catherine Chiron Rustem Khazipov Anna Kaminska Auditory stimuli mimicking ambient sounds drive temporal "delta-brushes" in premature infants.
description	In the premature infant, somatosensory and visual stimuli trigger an immature electroencephalographic (EEG) pattern, "delta-brushes," in the corresponding sensory cortical areas. Whether auditory stimuli evoke delta-brushes in the premature auditory cortex has not been reported. Here, responses to auditory stimuli were studied in 46 premature infants without neurologic risk aged 31 to 38 postmenstrual weeks (PMW) during routine EEG recording. Stimuli consisted of either low-volume technogenic "clicks" near the background noise level of the neonatal care unit, or a human voice at conversational sound level. Stimuli were administrated pseudo-randomly during quiet and active sleep. In another protocol, the cortical response to a composite stimulus ("click" and voice) was manually triggered during EEG hypoactive periods of quiet sleep. Cortical responses were analyzed by event detection, power frequency analysis and stimulus locked averaging. Before 34 PMW, both voice and "click" stimuli evoked cortical responses with similar frequency-power topographic characteristics, namely a temporal negative slow-wave and rapid oscillations similar to spontaneous delta-brushes. Responses to composite stimuli also showed a maximal frequency-power increase in temporal areas before 35 PMW. From 34 PMW the topography of responses in quiet sleep was different for "click" and voice stimuli: responses to "clicks" became diffuse but responses to voice remained limited to temporal areas. After the age of 35 PMW auditory evoked delta-brushes progressively disappeared and were replaced by a low amplitude response in the same location. Our data show that auditory stimuli mimicking ambient sounds efficiently evoke delta-brushes in temporal areas in the premature infant before 35 PMW. Along with findings in other sensory modalities (visual and somatosensory), these findings suggest that sensory driven delta-brushes represent a ubiquitous feature of the human sensory cortex during fetal stages and provide a potential test of functional cortical maturation during fetal development.
format	article
author	Mathilde Chipaux Matthew T Colonnese Audrey Mauguen Laure Fellous Mostafa Mokhtari Oscar Lezcano Mathieu Milh Olivier Dulac Catherine Chiron Rustem Khazipov Anna Kaminska
author_facet	Mathilde Chipaux Matthew T Colonnese Audrey Mauguen Laure Fellous Mostafa Mokhtari Oscar Lezcano Mathieu Milh Olivier Dulac Catherine Chiron Rustem Khazipov Anna Kaminska
author_sort	Mathilde Chipaux
title	Auditory stimuli mimicking ambient sounds drive temporal "delta-brushes" in premature infants.
title_short	Auditory stimuli mimicking ambient sounds drive temporal "delta-brushes" in premature infants.
title_full	Auditory stimuli mimicking ambient sounds drive temporal "delta-brushes" in premature infants.
title_fullStr	Auditory stimuli mimicking ambient sounds drive temporal "delta-brushes" in premature infants.
title_full_unstemmed	Auditory stimuli mimicking ambient sounds drive temporal "delta-brushes" in premature infants.
title_sort	auditory stimuli mimicking ambient sounds drive temporal "delta-brushes" in premature infants.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/5e8a07e153414a61a2b48f79962abe03
work_keys_str_mv	AT mathildechipaux auditorystimulimimickingambientsoundsdrivetemporaldeltabrushesinprematureinfants AT matthewtcolonnese auditorystimulimimickingambientsoundsdrivetemporaldeltabrushesinprematureinfants AT audreymauguen auditorystimulimimickingambientsoundsdrivetemporaldeltabrushesinprematureinfants AT laurefellous auditorystimulimimickingambientsoundsdrivetemporaldeltabrushesinprematureinfants AT mostafamokhtari auditorystimulimimickingambientsoundsdrivetemporaldeltabrushesinprematureinfants AT oscarlezcano auditorystimulimimickingambientsoundsdrivetemporaldeltabrushesinprematureinfants AT mathieumilh auditorystimulimimickingambientsoundsdrivetemporaldeltabrushesinprematureinfants AT olivierdulac auditorystimulimimickingambientsoundsdrivetemporaldeltabrushesinprematureinfants AT catherinechiron auditorystimulimimickingambientsoundsdrivetemporaldeltabrushesinprematureinfants AT rustemkhazipov auditorystimulimimickingambientsoundsdrivetemporaldeltabrushesinprematureinfants AT annakaminska auditorystimulimimickingambientsoundsdrivetemporaldeltabrushesinprematureinfants
_version_	1718421323111202816

Auditory stimuli mimicking ambient sounds drive temporal "delta-brushes" in premature infants.

Ejemplares similares