Assessment of specific toxicity of the complex remedy "Pancreophyt"

The experiments were carried out on white Wistar rats. The probable embryotoxic, teratogenic and fetotoxical influences of the plant remedy "Pancreophyt" at the doses of300 (1/10 DL50) and 600 mg/kg (1/5 DL50) were studied. The findings have shown that all indices of embryo lethality (the...

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Autores principales:	Y. G. Razuvaeva, V. V. Ayusheeva, I. G. Nikolaeva
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2015
Materias:	plant remedy “pancreophyt" embryotoxicity teratogenicity foetotoxicity the postnatal development Science Q
Acceso en línea:	https://doaj.org/article/5e93339078a1413f9cc5de334c8fb2d8
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spelling	oai:doaj.org-article:5e93339078a1413f9cc5de334c8fb2d82021-11-23T06:14:32ZAssessment of specific toxicity of the complex remedy "Pancreophyt"2541-94202587-9596https://doaj.org/article/5e93339078a1413f9cc5de334c8fb2d82015-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/38https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The experiments were carried out on white Wistar rats. The probable embryotoxic, teratogenic and fetotoxical influences of the plant remedy "Pancreophyt" at the doses of300 (1/10 DL50) and 600 mg/kg (1/5 DL50) were studied. The findings have shown that all indices of embryo lethality (the number of implantation sites, the number of alive fetus and the number of resorptions) in female white rats treated with the "Pancreophyt" do not differ significantly from the indices of the control group. The mass and craniocaudal dimensions of the fetus in the experimental group corresponded to the indices in the control group. In the second set of experiments the influence of the "Pancreophyt" (300 mg/kg) on the postnatal development of white rat offspring was studied. It was revealed that the death of infant rats was noted only on the 1st day of observation and was 4,7%; the liveweight gain and linear size of infant rats do not differ from the indices of those in the control group.Y. G. RazuvaevaV. V. AyusheevaI. G. NikolaevaScientific Сentre for Family Health and Human Reproduction Problemsarticleplant remedy “pancreophyt"embryotoxicityteratogenicityfoetotoxicitythe postnatal developmentScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2, Pp 85-88 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	plant remedy “pancreophyt" embryotoxicity teratogenicity foetotoxicity the postnatal development Science Q
spellingShingle	plant remedy “pancreophyt" embryotoxicity teratogenicity foetotoxicity the postnatal development Science Q Y. G. Razuvaeva V. V. Ayusheeva I. G. Nikolaeva Assessment of specific toxicity of the complex remedy "Pancreophyt"
description	The experiments were carried out on white Wistar rats. The probable embryotoxic, teratogenic and fetotoxical influences of the plant remedy "Pancreophyt" at the doses of300 (1/10 DL50) and 600 mg/kg (1/5 DL50) were studied. The findings have shown that all indices of embryo lethality (the number of implantation sites, the number of alive fetus and the number of resorptions) in female white rats treated with the "Pancreophyt" do not differ significantly from the indices of the control group. The mass and craniocaudal dimensions of the fetus in the experimental group corresponded to the indices in the control group. In the second set of experiments the influence of the "Pancreophyt" (300 mg/kg) on the postnatal development of white rat offspring was studied. It was revealed that the death of infant rats was noted only on the 1st day of observation and was 4,7%; the liveweight gain and linear size of infant rats do not differ from the indices of those in the control group.
format	article
author	Y. G. Razuvaeva V. V. Ayusheeva I. G. Nikolaeva
author_facet	Y. G. Razuvaeva V. V. Ayusheeva I. G. Nikolaeva
author_sort	Y. G. Razuvaeva
title	Assessment of specific toxicity of the complex remedy "Pancreophyt"
title_short	Assessment of specific toxicity of the complex remedy "Pancreophyt"
title_full	Assessment of specific toxicity of the complex remedy "Pancreophyt"
title_fullStr	Assessment of specific toxicity of the complex remedy "Pancreophyt"
title_full_unstemmed	Assessment of specific toxicity of the complex remedy "Pancreophyt"
title_sort	assessment of specific toxicity of the complex remedy "pancreophyt"
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2015
url	https://doaj.org/article/5e93339078a1413f9cc5de334c8fb2d8
work_keys_str_mv	AT ygrazuvaeva assessmentofspecifictoxicityofthecomplexremedypancreophyt AT vvayusheeva assessmentofspecifictoxicityofthecomplexremedypancreophyt AT ignikolaeva assessmentofspecifictoxicityofthecomplexremedypancreophyt
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Assessment of specific toxicity of the complex remedy "Pancreophyt"

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