Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer’s disease brains

Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer’s disease brains

Abstract Gadolinium (Gd)-stained MRI is based on Gd contrast agent (CA) administration into the brain parenchyma. The strong signal increase induced by Gd CA can be converted into resolution enhancement to record microscopic MR images. Moreover, inhomogeneous distribution of the Gd CA in the brain i...

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Autores principales: Clémence Dudeffant, Matthias Vandesquille, Kelly Herbert, Clément M. Garin, Sandro Alves, Véronique Blanchard, Emmanuel E. Comoy, Fanny Petit, Marc Dhenain
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/5e93a4a65928455e9bb7593b8b3d98c9
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