Molecular basis for PICS-mediated piRNA biogenesis and cell division

C. elegans piRNA biogenesis and chromosome segregation (PICS) complex is composed of TOFU-6, PICS-1, ERH-2, and two mutually exclusive factors PID-1 and TOST-1. By employing biochemical, structural, and cellular biology methods, the authors show that the PICS complex is an octamer consisting of two...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Xiaoyang Wang, Chenming Zeng, Shanhui Liao, Zhongliang Zhu, Jiahai Zhang, Xiaoming Tu, Xuebiao Yao, Xuezhu Feng, Shouhong Guang, Chao Xu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5e96c505b8154245861d516cea7565ea
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5e96c505b8154245861d516cea7565ea
record_format	dspace
spelling	oai:doaj.org-article:5e96c505b8154245861d516cea7565ea2021-12-02T18:14:09ZMolecular basis for PICS-mediated piRNA biogenesis and cell division10.1038/s41467-021-25896-72041-1723https://doaj.org/article/5e96c505b8154245861d516cea7565ea2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25896-7https://doaj.org/toc/2041-1723C. elegans piRNA biogenesis and chromosome segregation (PICS) complex is composed of TOFU-6, PICS-1, ERH-2, and two mutually exclusive factors PID-1 and TOST-1. By employing biochemical, structural, and cellular biology methods, the authors show that the PICS complex is an octamer consisting of two copies of each subunit, and functions in piRNA biogenesis and mitosis.Xiaoyang WangChenming ZengShanhui LiaoZhongliang ZhuJiahai ZhangXiaoming TuXuebiao YaoXuezhu FengShouhong GuangChao XuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiaoyang Wang Chenming Zeng Shanhui Liao Zhongliang Zhu Jiahai Zhang Xiaoming Tu Xuebiao Yao Xuezhu Feng Shouhong Guang Chao Xu Molecular basis for PICS-mediated piRNA biogenesis and cell division
description	C. elegans piRNA biogenesis and chromosome segregation (PICS) complex is composed of TOFU-6, PICS-1, ERH-2, and two mutually exclusive factors PID-1 and TOST-1. By employing biochemical, structural, and cellular biology methods, the authors show that the PICS complex is an octamer consisting of two copies of each subunit, and functions in piRNA biogenesis and mitosis.
format	article
author	Xiaoyang Wang Chenming Zeng Shanhui Liao Zhongliang Zhu Jiahai Zhang Xiaoming Tu Xuebiao Yao Xuezhu Feng Shouhong Guang Chao Xu
author_facet	Xiaoyang Wang Chenming Zeng Shanhui Liao Zhongliang Zhu Jiahai Zhang Xiaoming Tu Xuebiao Yao Xuezhu Feng Shouhong Guang Chao Xu
author_sort	Xiaoyang Wang
title	Molecular basis for PICS-mediated piRNA biogenesis and cell division
title_short	Molecular basis for PICS-mediated piRNA biogenesis and cell division
title_full	Molecular basis for PICS-mediated piRNA biogenesis and cell division
title_fullStr	Molecular basis for PICS-mediated piRNA biogenesis and cell division
title_full_unstemmed	Molecular basis for PICS-mediated piRNA biogenesis and cell division
title_sort	molecular basis for pics-mediated pirna biogenesis and cell division
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5e96c505b8154245861d516cea7565ea
work_keys_str_mv	AT xiaoyangwang molecularbasisforpicsmediatedpirnabiogenesisandcelldivision AT chenmingzeng molecularbasisforpicsmediatedpirnabiogenesisandcelldivision AT shanhuiliao molecularbasisforpicsmediatedpirnabiogenesisandcelldivision AT zhongliangzhu molecularbasisforpicsmediatedpirnabiogenesisandcelldivision AT jiahaizhang molecularbasisforpicsmediatedpirnabiogenesisandcelldivision AT xiaomingtu molecularbasisforpicsmediatedpirnabiogenesisandcelldivision AT xuebiaoyao molecularbasisforpicsmediatedpirnabiogenesisandcelldivision AT xuezhufeng molecularbasisforpicsmediatedpirnabiogenesisandcelldivision AT shouhongguang molecularbasisforpicsmediatedpirnabiogenesisandcelldivision AT chaoxu molecularbasisforpicsmediatedpirnabiogenesisandcelldivision
_version_	1718378454499459072

Molecular basis for PICS-mediated piRNA biogenesis and cell division

Ejemplares similares