Molecular basis for PICS-mediated piRNA biogenesis and cell division

Molecular basis for PICS-mediated piRNA biogenesis and cell division

C. elegans piRNA biogenesis and chromosome segregation (PICS) complex is composed of TOFU-6, PICS-1, ERH-2, and two mutually exclusive factors PID-1 and TOST-1. By employing biochemical, structural, and cellular biology methods, the authors show that the PICS complex is an octamer consisting of two...

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Main Authors: Xiaoyang Wang, Chenming Zeng, Shanhui Liao, Zhongliang Zhu, Jiahai Zhang, Xiaoming Tu, Xuebiao Yao, Xuezhu Feng, Shouhong Guang, Chao Xu
Format: article
Language:EN
Published: Nature Portfolio 2021
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Science
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Online Access:https://doaj.org/article/5e96c505b8154245861d516cea7565ea
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