Early dorsomedial tissue interactions regulate gyrification of distal neocortex

The contribution of long-range signaling to cortical gyrification remains poorly understood. In this study, authors demonstrate that the combined genetic loss of transcription factors Lmx1a and Lmx1b, expressed in the telencephalic dorsal midline neuroepithelium and head mesenchyme, respectively, in...

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Autores principales: Victor V. Chizhikov, Igor Y. Iskusnykh, Ekaterina Y. Steshina, Nikolai Fattakhov, Anne G. Lindgren, Ashwin S. Shetty, Achira Roy, Shubha Tole, Kathleen J. Millen
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/5e9a3cae7cdf4bcbae7688176c6be113
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spelling oai:doaj.org-article:5e9a3cae7cdf4bcbae7688176c6be1132021-12-02T14:39:56ZEarly dorsomedial tissue interactions regulate gyrification of distal neocortex10.1038/s41467-019-12913-z2041-1723https://doaj.org/article/5e9a3cae7cdf4bcbae7688176c6be1132019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12913-zhttps://doaj.org/toc/2041-1723The contribution of long-range signaling to cortical gyrification remains poorly understood. In this study, authors demonstrate that the combined genetic loss of transcription factors Lmx1a and Lmx1b, expressed in the telencephalic dorsal midline neuroepithelium and head mesenchyme, respectively, induces gyrification in the mouse neocortexVictor V. ChizhikovIgor Y. IskusnykhEkaterina Y. SteshinaNikolai FattakhovAnne G. LindgrenAshwin S. ShettyAchira RoyShubha ToleKathleen J. MillenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Victor V. Chizhikov
Igor Y. Iskusnykh
Ekaterina Y. Steshina
Nikolai Fattakhov
Anne G. Lindgren
Ashwin S. Shetty
Achira Roy
Shubha Tole
Kathleen J. Millen
Early dorsomedial tissue interactions regulate gyrification of distal neocortex
description The contribution of long-range signaling to cortical gyrification remains poorly understood. In this study, authors demonstrate that the combined genetic loss of transcription factors Lmx1a and Lmx1b, expressed in the telencephalic dorsal midline neuroepithelium and head mesenchyme, respectively, induces gyrification in the mouse neocortex
format article
author Victor V. Chizhikov
Igor Y. Iskusnykh
Ekaterina Y. Steshina
Nikolai Fattakhov
Anne G. Lindgren
Ashwin S. Shetty
Achira Roy
Shubha Tole
Kathleen J. Millen
author_facet Victor V. Chizhikov
Igor Y. Iskusnykh
Ekaterina Y. Steshina
Nikolai Fattakhov
Anne G. Lindgren
Ashwin S. Shetty
Achira Roy
Shubha Tole
Kathleen J. Millen
author_sort Victor V. Chizhikov
title Early dorsomedial tissue interactions regulate gyrification of distal neocortex
title_short Early dorsomedial tissue interactions regulate gyrification of distal neocortex
title_full Early dorsomedial tissue interactions regulate gyrification of distal neocortex
title_fullStr Early dorsomedial tissue interactions regulate gyrification of distal neocortex
title_full_unstemmed Early dorsomedial tissue interactions regulate gyrification of distal neocortex
title_sort early dorsomedial tissue interactions regulate gyrification of distal neocortex
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/5e9a3cae7cdf4bcbae7688176c6be113
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