Early dorsomedial tissue interactions regulate gyrification of distal neocortex
The contribution of long-range signaling to cortical gyrification remains poorly understood. In this study, authors demonstrate that the combined genetic loss of transcription factors Lmx1a and Lmx1b, expressed in the telencephalic dorsal midline neuroepithelium and head mesenchyme, respectively, in...
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Nature Portfolio
2019
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oai:doaj.org-article:5e9a3cae7cdf4bcbae7688176c6be1132021-12-02T14:39:56ZEarly dorsomedial tissue interactions regulate gyrification of distal neocortex10.1038/s41467-019-12913-z2041-1723https://doaj.org/article/5e9a3cae7cdf4bcbae7688176c6be1132019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12913-zhttps://doaj.org/toc/2041-1723The contribution of long-range signaling to cortical gyrification remains poorly understood. In this study, authors demonstrate that the combined genetic loss of transcription factors Lmx1a and Lmx1b, expressed in the telencephalic dorsal midline neuroepithelium and head mesenchyme, respectively, induces gyrification in the mouse neocortexVictor V. ChizhikovIgor Y. IskusnykhEkaterina Y. SteshinaNikolai FattakhovAnne G. LindgrenAshwin S. ShettyAchira RoyShubha ToleKathleen J. MillenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Victor V. Chizhikov Igor Y. Iskusnykh Ekaterina Y. Steshina Nikolai Fattakhov Anne G. Lindgren Ashwin S. Shetty Achira Roy Shubha Tole Kathleen J. Millen Early dorsomedial tissue interactions regulate gyrification of distal neocortex |
description |
The contribution of long-range signaling to cortical gyrification remains poorly understood. In this study, authors demonstrate that the combined genetic loss of transcription factors Lmx1a and Lmx1b, expressed in the telencephalic dorsal midline neuroepithelium and head mesenchyme, respectively, induces gyrification in the mouse neocortex |
format |
article |
author |
Victor V. Chizhikov Igor Y. Iskusnykh Ekaterina Y. Steshina Nikolai Fattakhov Anne G. Lindgren Ashwin S. Shetty Achira Roy Shubha Tole Kathleen J. Millen |
author_facet |
Victor V. Chizhikov Igor Y. Iskusnykh Ekaterina Y. Steshina Nikolai Fattakhov Anne G. Lindgren Ashwin S. Shetty Achira Roy Shubha Tole Kathleen J. Millen |
author_sort |
Victor V. Chizhikov |
title |
Early dorsomedial tissue interactions regulate gyrification of distal neocortex |
title_short |
Early dorsomedial tissue interactions regulate gyrification of distal neocortex |
title_full |
Early dorsomedial tissue interactions regulate gyrification of distal neocortex |
title_fullStr |
Early dorsomedial tissue interactions regulate gyrification of distal neocortex |
title_full_unstemmed |
Early dorsomedial tissue interactions regulate gyrification of distal neocortex |
title_sort |
early dorsomedial tissue interactions regulate gyrification of distal neocortex |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/5e9a3cae7cdf4bcbae7688176c6be113 |
work_keys_str_mv |
AT victorvchizhikov earlydorsomedialtissueinteractionsregulategyrificationofdistalneocortex AT igoryiskusnykh earlydorsomedialtissueinteractionsregulategyrificationofdistalneocortex AT ekaterinaysteshina earlydorsomedialtissueinteractionsregulategyrificationofdistalneocortex AT nikolaifattakhov earlydorsomedialtissueinteractionsregulategyrificationofdistalneocortex AT anneglindgren earlydorsomedialtissueinteractionsregulategyrificationofdistalneocortex AT ashwinsshetty earlydorsomedialtissueinteractionsregulategyrificationofdistalneocortex AT achiraroy earlydorsomedialtissueinteractionsregulategyrificationofdistalneocortex AT shubhatole earlydorsomedialtissueinteractionsregulategyrificationofdistalneocortex AT kathleenjmillen earlydorsomedialtissueinteractionsregulategyrificationofdistalneocortex |
_version_ |
1718390473957048320 |