Squamous cell carcinoma: variation on dermatoscopy vascular features between well and non-well differentiated tumors

Objective: Compare the dermatoscopy vascular features of well differentiated with non-well differentiated squamous cell carcinoma (SCC). Design: A prospective study of 294 consecutive cases of histopathologically confirmed invasive SCC compared the dermatoscopic vascular features of well to comb...

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Autores principales:	John Pyne, Devendra Sapkota, Jian Cheng Wong
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2012
Materias:	squamous cell carcinoma well moderate poor differentiation vascular Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/5e9ccbf74f83446ca7a0d26b958e9bc4
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spelling	oai:doaj.org-article:5e9ccbf74f83446ca7a0d26b958e9bc42021-11-17T08:33:00ZSquamous cell carcinoma: variation on dermatoscopy vascular features between well and non-well differentiated tumors2160-9381https://doaj.org/article/5e9ccbf74f83446ca7a0d26b958e9bc42012-10-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/982https://doaj.org/toc/2160-9381 Objective: Compare the dermatoscopy vascular features of well differentiated with non-well differentiated squamous cell carcinoma (SCC). Design: A prospective study of 294 consecutive cases of histopathologically confirmed invasive SCC compared the dermatoscopic vascular features of well to combined moderate and poorly differentiated tumors. These features were recorded live directly from the patients and included: the percentage of pink in the tumor, the presence of branching, serpentine, dot, hairpin, glomerular and linear vessels, and the number of these vessel types present within each tumor. Vessel types were also reviewed by tumor depth in 1 mm increments. Setting: Two medical practices in Sydney, Australia. Patients: Eighty-six female and 208 male patients (29-95 years old). Main outcome measure: Dermatoscopic vascular feature variation between grades of tumor differentiation and tumor depth. Results: Of 294 invasive SCCs, 255 (87%) were well differentiated, 32 (11%) were moderately differentiated and 7 (2%) were poorly differentiated. The percentage of pink areas within tumors varied between differentiation grades. The combined group of moderate and poorly differentiated tumors displayed more branching (28%, P<0.001) and serpentine (62%, P<0.005) blood vessels compared to well differentiated tumors (8% and 38%, respectively). Moderate and poorly differentiated tumors displayed larger numbers of vessel types (3.3) compared to well differentiated tumors (2.6, P < 0.01). Branching and serpentine vessels both increased in incidence with increasing tumor depth (p<0.05). Conclusion: Grades of tumor differentiation in SCC display varying dermatoscopic vascular features. The incidence of branching and serpentine vessels increases with increasing tumor depth and the shift towards poor differentiation. John PyneDevendra SapkotaJian Cheng WongMattioli1885articlesquamous cell carcinomawellmoderatepoordifferentiationvascularDermatologyRL1-803ENDermatology Practical & Conceptual (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	squamous cell carcinoma well moderate poor differentiation vascular Dermatology RL1-803
spellingShingle	squamous cell carcinoma well moderate poor differentiation vascular Dermatology RL1-803 John Pyne Devendra Sapkota Jian Cheng Wong Squamous cell carcinoma: variation on dermatoscopy vascular features between well and non-well differentiated tumors
description	Objective: Compare the dermatoscopy vascular features of well differentiated with non-well differentiated squamous cell carcinoma (SCC). Design: A prospective study of 294 consecutive cases of histopathologically confirmed invasive SCC compared the dermatoscopic vascular features of well to combined moderate and poorly differentiated tumors. These features were recorded live directly from the patients and included: the percentage of pink in the tumor, the presence of branching, serpentine, dot, hairpin, glomerular and linear vessels, and the number of these vessel types present within each tumor. Vessel types were also reviewed by tumor depth in 1 mm increments. Setting: Two medical practices in Sydney, Australia. Patients: Eighty-six female and 208 male patients (29-95 years old). Main outcome measure: Dermatoscopic vascular feature variation between grades of tumor differentiation and tumor depth. Results: Of 294 invasive SCCs, 255 (87%) were well differentiated, 32 (11%) were moderately differentiated and 7 (2%) were poorly differentiated. The percentage of pink areas within tumors varied between differentiation grades. The combined group of moderate and poorly differentiated tumors displayed more branching (28%, P<0.001) and serpentine (62%, P<0.005) blood vessels compared to well differentiated tumors (8% and 38%, respectively). Moderate and poorly differentiated tumors displayed larger numbers of vessel types (3.3) compared to well differentiated tumors (2.6, P < 0.01). Branching and serpentine vessels both increased in incidence with increasing tumor depth (p<0.05). Conclusion: Grades of tumor differentiation in SCC display varying dermatoscopic vascular features. The incidence of branching and serpentine vessels increases with increasing tumor depth and the shift towards poor differentiation.
format	article
author	John Pyne Devendra Sapkota Jian Cheng Wong
author_facet	John Pyne Devendra Sapkota Jian Cheng Wong
author_sort	John Pyne
title	Squamous cell carcinoma: variation on dermatoscopy vascular features between well and non-well differentiated tumors
title_short	Squamous cell carcinoma: variation on dermatoscopy vascular features between well and non-well differentiated tumors
title_full	Squamous cell carcinoma: variation on dermatoscopy vascular features between well and non-well differentiated tumors
title_fullStr	Squamous cell carcinoma: variation on dermatoscopy vascular features between well and non-well differentiated tumors
title_full_unstemmed	Squamous cell carcinoma: variation on dermatoscopy vascular features between well and non-well differentiated tumors
title_sort	squamous cell carcinoma: variation on dermatoscopy vascular features between well and non-well differentiated tumors
publisher	Mattioli1885
publishDate	2012
url	https://doaj.org/article/5e9ccbf74f83446ca7a0d26b958e9bc4
work_keys_str_mv	AT johnpyne squamouscellcarcinomavariationondermatoscopyvascularfeaturesbetweenwellandnonwelldifferentiatedtumors AT devendrasapkota squamouscellcarcinomavariationondermatoscopyvascularfeaturesbetweenwellandnonwelldifferentiatedtumors AT jianchengwong squamouscellcarcinomavariationondermatoscopyvascularfeaturesbetweenwellandnonwelldifferentiatedtumors
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Squamous cell carcinoma: variation on dermatoscopy vascular features between well and non-well differentiated tumors

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