Scientific and practical approaches to optimizing the pharmaceutical supply of pediatric palliative patients with paralytic syndromes

Today, palliative care (PC) as a system has a complex structure with stable orderliness, interrelated elements and subsystems. The problem of providing PD with an appropriate level and quality to the children population is particularly acute; it is due to differences in the duration of provision, th...

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Autores principales: I. V. Kubarieva, M. S. Beketova
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Lenguaje:UK
Publicado: The State Expert Center of the Ministry of Health of Ukraine 2021
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Acceso en línea:https://doaj.org/article/5ea17046cc45429e99a9aad4495a1832
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spelling oai:doaj.org-article:5ea17046cc45429e99a9aad4495a18322021-11-04T11:58:39ZScientific and practical approaches to optimizing the pharmaceutical supply of pediatric palliative patients with paralytic syndromes10.32352/0367-3057.5.21.010367-30572617-9628https://doaj.org/article/5ea17046cc45429e99a9aad4495a18322021-10-01T00:00:00Zhttps://pharmj.org.ua/index.php/journal/article/view/1245/1169https://doaj.org/toc/0367-3057https://doaj.org/toc/2617-9628Today, palliative care (PC) as a system has a complex structure with stable orderliness, interrelated elements and subsystems. The problem of providing PD with an appropriate level and quality to the children population is particularly acute; it is due to differences in the duration of provision, the necessity to provide educational services, and the socialization of palliative children. At the same time, an important aspect in achieving an appropriate quality of life for children and their families related to health is the assessment of not only medical and social, but also pharmaceutical provision. The aim of the work is to substantiate the approaches to optimization of pharmaceutical support of pediatric palliative patients with paralytic syndromes. The study objects were data from medical records, theactual consumption of medicines by pediatric patients of the Kharkiv healthcare institution where palliative care was provided, as well as data on the state registration of medicines in Ukraine. During the study, clinical and anamnestic, sociological, and marketing methods were used. Based on the results of the analysis of clinical and anamnestic data and the overall assessment of symptoms in a sample group of palliative children with paralytic syndromes, which was 115 people, pathological conditions that led to frequent or permanent distress were identified. Among them, the spastic syndrome prevailed in 100% of cases, the pain syndrome in 66% of cases, the convulsive syndrome in 59%, respectively, and digestive disorders were observed in 82.6% of patients in the sample. It was found that a large proportions of drugs for pharmacological correction of symptoms in the sample of patients were formed by antiepileptic drugs, laxatives and centrally acting muscle relaxants. The results of the marketing analysis of a definite segment of the pharmaceutical market showed a rather limited range of drugs for pediatric dosage forms and concentrations, and it on average ranged from 3.1% to 25% in the pharmacotherapeutic groups studied. Thus, the results obtained prove the need to develop mechanisms for optimizing the pharmaceutical supply of pediatric palliative patients, in particular, expanding the range of medicines approved for use in pediatric practice.I. V. KubarievaM. S. BeketovaThe State Expert Center of the Ministry of Health of Ukrainearticlepharmaceutical carepalliative careinfantile cerebral palsypalliative patientsTherapeutics. PharmacologyRM1-950Pharmacy and materia medicaRS1-441UKФармацевтичний журнал, Vol 5, Pp 7-15 (2021)
institution DOAJ
collection DOAJ
language UK
topic pharmaceutical care
palliative care
infantile cerebral palsy
palliative patients
Therapeutics. Pharmacology
RM1-950
Pharmacy and materia medica
RS1-441
spellingShingle pharmaceutical care
palliative care
infantile cerebral palsy
palliative patients
Therapeutics. Pharmacology
RM1-950
Pharmacy and materia medica
RS1-441
I. V. Kubarieva
M. S. Beketova
Scientific and practical approaches to optimizing the pharmaceutical supply of pediatric palliative patients with paralytic syndromes
description Today, palliative care (PC) as a system has a complex structure with stable orderliness, interrelated elements and subsystems. The problem of providing PD with an appropriate level and quality to the children population is particularly acute; it is due to differences in the duration of provision, the necessity to provide educational services, and the socialization of palliative children. At the same time, an important aspect in achieving an appropriate quality of life for children and their families related to health is the assessment of not only medical and social, but also pharmaceutical provision. The aim of the work is to substantiate the approaches to optimization of pharmaceutical support of pediatric palliative patients with paralytic syndromes. The study objects were data from medical records, theactual consumption of medicines by pediatric patients of the Kharkiv healthcare institution where palliative care was provided, as well as data on the state registration of medicines in Ukraine. During the study, clinical and anamnestic, sociological, and marketing methods were used. Based on the results of the analysis of clinical and anamnestic data and the overall assessment of symptoms in a sample group of palliative children with paralytic syndromes, which was 115 people, pathological conditions that led to frequent or permanent distress were identified. Among them, the spastic syndrome prevailed in 100% of cases, the pain syndrome in 66% of cases, the convulsive syndrome in 59%, respectively, and digestive disorders were observed in 82.6% of patients in the sample. It was found that a large proportions of drugs for pharmacological correction of symptoms in the sample of patients were formed by antiepileptic drugs, laxatives and centrally acting muscle relaxants. The results of the marketing analysis of a definite segment of the pharmaceutical market showed a rather limited range of drugs for pediatric dosage forms and concentrations, and it on average ranged from 3.1% to 25% in the pharmacotherapeutic groups studied. Thus, the results obtained prove the need to develop mechanisms for optimizing the pharmaceutical supply of pediatric palliative patients, in particular, expanding the range of medicines approved for use in pediatric practice.
format article
author I. V. Kubarieva
M. S. Beketova
author_facet I. V. Kubarieva
M. S. Beketova
author_sort I. V. Kubarieva
title Scientific and practical approaches to optimizing the pharmaceutical supply of pediatric palliative patients with paralytic syndromes
title_short Scientific and practical approaches to optimizing the pharmaceutical supply of pediatric palliative patients with paralytic syndromes
title_full Scientific and practical approaches to optimizing the pharmaceutical supply of pediatric palliative patients with paralytic syndromes
title_fullStr Scientific and practical approaches to optimizing the pharmaceutical supply of pediatric palliative patients with paralytic syndromes
title_full_unstemmed Scientific and practical approaches to optimizing the pharmaceutical supply of pediatric palliative patients with paralytic syndromes
title_sort scientific and practical approaches to optimizing the pharmaceutical supply of pediatric palliative patients with paralytic syndromes
publisher The State Expert Center of the Ministry of Health of Ukraine
publishDate 2021
url https://doaj.org/article/5ea17046cc45429e99a9aad4495a1832
work_keys_str_mv AT ivkubarieva scientificandpracticalapproachestooptimizingthepharmaceuticalsupplyofpediatricpalliativepatientswithparalyticsyndromes
AT msbeketova scientificandpracticalapproachestooptimizingthepharmaceuticalsupplyofpediatricpalliativepatientswithparalyticsyndromes
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