A mathematical model of tumor regression and recurrence after therapeutic oncogene inactivation
Abstract The targeted inactivation of individual oncogenes can elicit regression of cancers through a phenomenon called oncogene addiction. Oncogene addiction is mediated by cell-autonomous and immune-dependent mechanisms. Therapeutic resistance to oncogene inactivation leads to recurrence but can b...
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Autores principales: | Sharon S. Hori, Ling Tong, Srividya Swaminathan, Mariola Liebersbach, Jingjing Wang, Sanjiv S. Gambhir, Dean W. Felsher |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/5eaa4c551c6b436ebaa97bfaaabc2d0e |
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