A mathematical model of tumor regression and recurrence after therapeutic oncogene inactivation

Abstract The targeted inactivation of individual oncogenes can elicit regression of cancers through a phenomenon called oncogene addiction. Oncogene addiction is mediated by cell-autonomous and immune-dependent mechanisms. Therapeutic resistance to oncogene inactivation leads to recurrence but can b...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sharon S. Hori, Ling Tong, Srividya Swaminathan, Mariola Liebersbach, Jingjing Wang, Sanjiv S. Gambhir, Dean W. Felsher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/5eaa4c551c6b436ebaa97bfaaabc2d0e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares