Sec16 alternative splicing dynamically controls COPII transport efficiency

The transport of secretory proteins from the endoplasmic reticulum to the Golgi depends on COPII-coated vesicles. Here, the authors show that activation-induced alternative splicing of Sec16 controls adaptation of COPII transport to increased secretory cargo upon T cell activation.

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Autores principales:	Ilka Wilhelmi, Regina Kanski, Alexander Neumann, Olga Herdt, Florian Hoff, Ralf Jacob, Marco Preußner, Florian Heyd
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5eac4601c94e4e0ea0fcc66ec338cff3
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spelling	oai:doaj.org-article:5eac4601c94e4e0ea0fcc66ec338cff32021-12-02T14:38:57ZSec16 alternative splicing dynamically controls COPII transport efficiency10.1038/ncomms123472041-1723https://doaj.org/article/5eac4601c94e4e0ea0fcc66ec338cff32016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12347https://doaj.org/toc/2041-1723The transport of secretory proteins from the endoplasmic reticulum to the Golgi depends on COPII-coated vesicles. Here, the authors show that activation-induced alternative splicing of Sec16 controls adaptation of COPII transport to increased secretory cargo upon T cell activation.Ilka WilhelmiRegina KanskiAlexander NeumannOlga HerdtFlorian HoffRalf JacobMarco PreußnerFlorian HeydNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ilka Wilhelmi Regina Kanski Alexander Neumann Olga Herdt Florian Hoff Ralf Jacob Marco Preußner Florian Heyd Sec16 alternative splicing dynamically controls COPII transport efficiency
description	The transport of secretory proteins from the endoplasmic reticulum to the Golgi depends on COPII-coated vesicles. Here, the authors show that activation-induced alternative splicing of Sec16 controls adaptation of COPII transport to increased secretory cargo upon T cell activation.
format	article
author	Ilka Wilhelmi Regina Kanski Alexander Neumann Olga Herdt Florian Hoff Ralf Jacob Marco Preußner Florian Heyd
author_facet	Ilka Wilhelmi Regina Kanski Alexander Neumann Olga Herdt Florian Hoff Ralf Jacob Marco Preußner Florian Heyd
author_sort	Ilka Wilhelmi
title	Sec16 alternative splicing dynamically controls COPII transport efficiency
title_short	Sec16 alternative splicing dynamically controls COPII transport efficiency
title_full	Sec16 alternative splicing dynamically controls COPII transport efficiency
title_fullStr	Sec16 alternative splicing dynamically controls COPII transport efficiency
title_full_unstemmed	Sec16 alternative splicing dynamically controls COPII transport efficiency
title_sort	sec16 alternative splicing dynamically controls copii transport efficiency
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/5eac4601c94e4e0ea0fcc66ec338cff3
work_keys_str_mv	AT ilkawilhelmi sec16alternativesplicingdynamicallycontrolscopiitransportefficiency AT reginakanski sec16alternativesplicingdynamicallycontrolscopiitransportefficiency AT alexanderneumann sec16alternativesplicingdynamicallycontrolscopiitransportefficiency AT olgaherdt sec16alternativesplicingdynamicallycontrolscopiitransportefficiency AT florianhoff sec16alternativesplicingdynamicallycontrolscopiitransportefficiency AT ralfjacob sec16alternativesplicingdynamicallycontrolscopiitransportefficiency AT marcopreußner sec16alternativesplicingdynamicallycontrolscopiitransportefficiency AT florianheyd sec16alternativesplicingdynamicallycontrolscopiitransportefficiency
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Sec16 alternative splicing dynamically controls COPII transport efficiency

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