Anxiety enhances pain in a model of osteoarthritis and is associated with altered endogenous opioid function and reduced opioid analgesia
Abstract. Introduction:. Negative affect, including anxiety and depression, is prevalent in chronic pain states such as osteoarthritis (OA) and associated with greater use of opioid analgesics, potentially contributing to present and future opioid crises. Objectives:. We tested the hypothesis that t...
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| Main Authors: | , , , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Wolters Kluwer
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/5ec1331b06bf473e8821f26c427d8514 |
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