EFFECT OF ESTRIOL ON THE FUNCTIONAL ACTIVITY OF MONOCYTES IN VITRO

Abstract. Employing an in vitro cellular system, we have studied effects of estriol at physiological concentrations corresponding to the 1st, 2nd , and 3rd trimesters of pregnancy upon phagocytic, bactericidal activity of monocytes, and their ability to form extracellular traps. This steroid hormone...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	I. I. Dolgushin, T. G. Smirnova, A. Yu. Savochkina, Yu. S. Shishkova, O. B. Prokopyeva, E. A. Mezentseva
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	monocyte extracellular traps4 estriol phagocytosis Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/5ec83752802545769642f7f95edc8476
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5ec83752802545769642f7f95edc8476
record_format	dspace
spelling	oai:doaj.org-article:5ec83752802545769642f7f95edc84762021-11-18T08:03:40ZEFFECT OF ESTRIOL ON THE FUNCTIONAL ACTIVITY OF MONOCYTES IN VITRO1563-06252313-741X10.15789/1563-0625-2012-4-5-429-432https://doaj.org/article/5ec83752802545769642f7f95edc84762014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/372https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Employing an in vitro cellular system, we have studied effects of estriol at physiological concentrations corresponding to the 1st, 2nd , and 3rd trimesters of pregnancy upon phagocytic, bactericidal activity of monocytes, and their ability to form extracellular traps. This steroid hormone does not significantly affect phagocytic function of monocytes at concentrations corresponding to the 1st, 2nd , and 3rd trimesters of pregnancy, however, leads to increased formation of extracellular traps and increase of oxygen-dependent bactericidal effects.I. I. DolgushinT. G. SmirnovaA. Yu. SavochkinaYu. S. ShishkovaO. B. ProkopyevaE. A. MezentsevaSPb RAACIarticlemonocyte extracellular traps4 estriolphagocytosisImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 14, Iss 4-5, Pp 429-432 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	monocyte extracellular traps4 estriol phagocytosis Immunologic diseases. Allergy RC581-607
spellingShingle	monocyte extracellular traps4 estriol phagocytosis Immunologic diseases. Allergy RC581-607 I. I. Dolgushin T. G. Smirnova A. Yu. Savochkina Yu. S. Shishkova O. B. Prokopyeva E. A. Mezentseva EFFECT OF ESTRIOL ON THE FUNCTIONAL ACTIVITY OF MONOCYTES IN VITRO
description	Abstract. Employing an in vitro cellular system, we have studied effects of estriol at physiological concentrations corresponding to the 1st, 2nd , and 3rd trimesters of pregnancy upon phagocytic, bactericidal activity of monocytes, and their ability to form extracellular traps. This steroid hormone does not significantly affect phagocytic function of monocytes at concentrations corresponding to the 1st, 2nd , and 3rd trimesters of pregnancy, however, leads to increased formation of extracellular traps and increase of oxygen-dependent bactericidal effects.
format	article
author	I. I. Dolgushin T. G. Smirnova A. Yu. Savochkina Yu. S. Shishkova O. B. Prokopyeva E. A. Mezentseva
author_facet	I. I. Dolgushin T. G. Smirnova A. Yu. Savochkina Yu. S. Shishkova O. B. Prokopyeva E. A. Mezentseva
author_sort	I. I. Dolgushin
title	EFFECT OF ESTRIOL ON THE FUNCTIONAL ACTIVITY OF MONOCYTES IN VITRO
title_short	EFFECT OF ESTRIOL ON THE FUNCTIONAL ACTIVITY OF MONOCYTES IN VITRO
title_full	EFFECT OF ESTRIOL ON THE FUNCTIONAL ACTIVITY OF MONOCYTES IN VITRO
title_fullStr	EFFECT OF ESTRIOL ON THE FUNCTIONAL ACTIVITY OF MONOCYTES IN VITRO
title_full_unstemmed	EFFECT OF ESTRIOL ON THE FUNCTIONAL ACTIVITY OF MONOCYTES IN VITRO
title_sort	effect of estriol on the functional activity of monocytes in vitro
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/5ec83752802545769642f7f95edc8476
work_keys_str_mv	AT iidolgushin effectofestriolonthefunctionalactivityofmonocytesinvitro AT tgsmirnova effectofestriolonthefunctionalactivityofmonocytesinvitro AT ayusavochkina effectofestriolonthefunctionalactivityofmonocytesinvitro AT yusshishkova effectofestriolonthefunctionalactivityofmonocytesinvitro AT obprokopyeva effectofestriolonthefunctionalactivityofmonocytesinvitro AT eamezentseva effectofestriolonthefunctionalactivityofmonocytesinvitro
_version_	1718422478959673344

EFFECT OF ESTRIOL ON THE FUNCTIONAL ACTIVITY OF MONOCYTES IN VITRO

Ejemplares similares