Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis
Abstract Recent evidence indicates that single multiple sclerosis (MS) susceptibility genes involved in interferon (IFN) signaling display altered transcript levels in peripheral blood of untreated MS subjects, suggesting that responsiveness to endogenous IFN is dysregulated during neuroinflammation...
Enregistré dans:
Auteurs principaux: | Sundararajan Srinivasan, Martina Severa, Fabiana Rizzo, Ramesh Menon, Elena Brini, Rosella Mechelli, Vittorio Martinelli, Paul Hertzog, Marco Salvetti, Roberto Furlan, Gianvito Martino, Giancarlo Comi, Eliana M. Coccia, Cinthia Farina |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/5eca37b29ea3460fbd37602ded3bbfa2 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Author Correction: Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis
par: Sundararajan Srinivasan, et autres
Publié: (2018) -
Shared molecular and functional frameworks among five complex human disorders: a comparative study on interactomes linked to susceptibility genes.
par: Ramesh Menon, et autres
Publié: (2011) -
The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting.
par: Andrew E Shaw, et autres
Publié: (2021) -
Increased CD8+ T cell response to Epstein-Barr virus lytic antigens in the active phase of multiple sclerosis.
par: Daniela F Angelini, et autres
Publié: (2013) -
T regulatory cells are markers of disease activity in multiple sclerosis patients.
par: Dacia Dalla Libera, et autres
Publié: (2011)