Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis

Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis

Abstract Recent evidence indicates that single multiple sclerosis (MS) susceptibility genes involved in interferon (IFN) signaling display altered transcript levels in peripheral blood of untreated MS subjects, suggesting that responsiveness to endogenous IFN is dysregulated during neuroinflammation...

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Main Authors: Sundararajan Srinivasan, Martina Severa, Fabiana Rizzo, Ramesh Menon, Elena Brini, Rosella Mechelli, Vittorio Martinelli, Paul Hertzog, Marco Salvetti, Roberto Furlan, Gianvito Martino, Giancarlo Comi, Eliana M. Coccia, Cinthia Farina
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/5eca37b29ea3460fbd37602ded3bbfa2
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