Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies
The extracellular matrix (ECM) can influence tumor growth and its response to therapy. Here, the authors develop a fibrinogen and thrombin based artificial ECM that can starve tumours and prevent dissemination of cancer cells.
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Nature Portfolio
2020
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oai:doaj.org-article:5ecac35df00f43fe86be05abd44bbf7e2021-12-02T19:17:00ZControllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies10.1038/s41467-020-18493-72041-1723https://doaj.org/article/5ecac35df00f43fe86be05abd44bbf7e2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18493-7https://doaj.org/toc/2041-1723The extracellular matrix (ECM) can influence tumor growth and its response to therapy. Here, the authors develop a fibrinogen and thrombin based artificial ECM that can starve tumours and prevent dissemination of cancer cells.Di-Wei ZhengSheng HongQiu-Ling ZhangXue DongPei PanWen-Fang SongWen SongSi-Xue ChengXian-Zheng ZhangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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Science Q Di-Wei Zheng Sheng Hong Qiu-Ling Zhang Xue Dong Pei Pan Wen-Fang Song Wen Song Si-Xue Cheng Xian-Zheng Zhang Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies |
description |
The extracellular matrix (ECM) can influence tumor growth and its response to therapy. Here, the authors develop a fibrinogen and thrombin based artificial ECM that can starve tumours and prevent dissemination of cancer cells. |
format |
article |
author |
Di-Wei Zheng Sheng Hong Qiu-Ling Zhang Xue Dong Pei Pan Wen-Fang Song Wen Song Si-Xue Cheng Xian-Zheng Zhang |
author_facet |
Di-Wei Zheng Sheng Hong Qiu-Ling Zhang Xue Dong Pei Pan Wen-Fang Song Wen Song Si-Xue Cheng Xian-Zheng Zhang |
author_sort |
Di-Wei Zheng |
title |
Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies |
title_short |
Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies |
title_full |
Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies |
title_fullStr |
Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies |
title_full_unstemmed |
Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies |
title_sort |
controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/5ecac35df00f43fe86be05abd44bbf7e |
work_keys_str_mv |
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1718376914322718720 |