Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies

The extracellular matrix (ECM) can influence tumor growth and its response to therapy. Here, the authors develop a fibrinogen and thrombin based artificial ECM that can starve tumours and prevent dissemination of cancer cells.

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Autores principales: Di-Wei Zheng, Sheng Hong, Qiu-Ling Zhang, Xue Dong, Pei Pan, Wen-Fang Song, Wen Song, Si-Xue Cheng, Xian-Zheng Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/5ecac35df00f43fe86be05abd44bbf7e
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spelling oai:doaj.org-article:5ecac35df00f43fe86be05abd44bbf7e2021-12-02T19:17:00ZControllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies10.1038/s41467-020-18493-72041-1723https://doaj.org/article/5ecac35df00f43fe86be05abd44bbf7e2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18493-7https://doaj.org/toc/2041-1723The extracellular matrix (ECM) can influence tumor growth and its response to therapy. Here, the authors develop a fibrinogen and thrombin based artificial ECM that can starve tumours and prevent dissemination of cancer cells.Di-Wei ZhengSheng HongQiu-Ling ZhangXue DongPei PanWen-Fang SongWen SongSi-Xue ChengXian-Zheng ZhangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Di-Wei Zheng
Sheng Hong
Qiu-Ling Zhang
Xue Dong
Pei Pan
Wen-Fang Song
Wen Song
Si-Xue Cheng
Xian-Zheng Zhang
Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies
description The extracellular matrix (ECM) can influence tumor growth and its response to therapy. Here, the authors develop a fibrinogen and thrombin based artificial ECM that can starve tumours and prevent dissemination of cancer cells.
format article
author Di-Wei Zheng
Sheng Hong
Qiu-Ling Zhang
Xue Dong
Pei Pan
Wen-Fang Song
Wen Song
Si-Xue Cheng
Xian-Zheng Zhang
author_facet Di-Wei Zheng
Sheng Hong
Qiu-Ling Zhang
Xue Dong
Pei Pan
Wen-Fang Song
Wen Song
Si-Xue Cheng
Xian-Zheng Zhang
author_sort Di-Wei Zheng
title Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies
title_short Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies
title_full Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies
title_fullStr Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies
title_full_unstemmed Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies
title_sort controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/5ecac35df00f43fe86be05abd44bbf7e
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