Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module
Exosomes have been identified as promising vehicles for the in vivodelivery of therapeutic molecules. Here the authors design a system to load protein cargos into exosomes during their biogenesis using optogenetic control of protein-protein interactions between the cargo and an exosome-localized par...
Saved in:
Main Authors: | Nambin Yim, Seung-Wook Ryu, Kyungsun Choi, Kwang Ryeol Lee, Seunghee Lee, Hojun Choi, Jeongjin Kim, Mohammed R. Shaker, Woong Sun, Ji-Ho Park, Daesoo Kim, Won Do Heo, Chulhee Choi |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
|
Subjects: | |
Online Access: | https://doaj.org/article/5ecca384bd0343d7bad8c5a0f51a75de |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Intracellular delivery of cell-penetrating peptide-transcriptional factor fusion protein and its role in selective osteogenesis
by: Suh JS, et al.
Published: (2014) -
Transforming protein-polymer conjugate purification by tuning protein solubility
by: Stefanie L. Baker, et al.
Published: (2019) -
Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2
by: Hyerim Park, et al.
Published: (2017) -
Identification of the <i>Capsicum baccatum</i> NLR Protein CbAR9 Conferring Disease Resistance to Anthracnose
by: Seungmin Son, et al.
Published: (2021) -
Protein pI and Intracellular Localization
by: Alexander A. Tokmakov, et al.
Published: (2021)