Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module
Exosomes have been identified as promising vehicles for the in vivodelivery of therapeutic molecules. Here the authors design a system to load protein cargos into exosomes during their biogenesis using optogenetic control of protein-protein interactions between the cargo and an exosome-localized par...
Enregistré dans:
Auteurs principaux: | Nambin Yim, Seung-Wook Ryu, Kyungsun Choi, Kwang Ryeol Lee, Seunghee Lee, Hojun Choi, Jeongjin Kim, Mohammed R. Shaker, Woong Sun, Ji-Ho Park, Daesoo Kim, Won Do Heo, Chulhee Choi |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/5ecca384bd0343d7bad8c5a0f51a75de |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Intracellular delivery of cell-penetrating peptide-transcriptional factor fusion protein and its role in selective osteogenesis
par: Suh JS, et autres
Publié: (2014) -
Transforming protein-polymer conjugate purification by tuning protein solubility
par: Stefanie L. Baker, et autres
Publié: (2019) -
Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2
par: Hyerim Park, et autres
Publié: (2017) -
Identification of the <i>Capsicum baccatum</i> NLR Protein CbAR9 Conferring Disease Resistance to Anthracnose
par: Seungmin Son, et autres
Publié: (2021) -
Protein pI and Intracellular Localization
par: Alexander A. Tokmakov, et autres
Publié: (2021)