Pre-existing immunity and vaccine history determine hemagglutinin-specific CD4 T cell and IgG response following seasonal influenza vaccination

Understanding individual variations in the response to seasonal influenza vaccines has broad implications from basic immunology to public health. Here authors show that influenza hemagglutinin-specific T and B cell responses are determined by the pre-vaccination immune phenotype and vaccination hist...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Katharina Wild, Maike Smits, Saskia Killmer, Shirin Strohmeier, Christoph Neumann-Haefelin, Bertram Bengsch, Florian Krammer, Martin Schwemmle, Maike Hofmann, Robert Thimme, Katharina Zoldan, Tobias Boettler
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/5ecdcebcaf7d4d5180dbe8bfd157f337
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Understanding individual variations in the response to seasonal influenza vaccines has broad implications from basic immunology to public health. Here authors show that influenza hemagglutinin-specific T and B cell responses are determined by the pre-vaccination immune phenotype and vaccination history of recipients.