Identifying patients at high risk of breast cancer recurrence: strategies to improve patient outcomes
Yehoda M Martei,1 Jennifer M Matro1,21Department of Medicine, Hematology-Oncology Division, 2Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USAAbstract: Identifying patients at high risk of breast cancer recurrence has important implications not only for enabling the ability t...
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Dove Medical Press
2015
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oai:doaj.org-article:5ed92c546ad54a3981e868b4bf323c8f2021-12-02T00:33:08ZIdentifying patients at high risk of breast cancer recurrence: strategies to improve patient outcomes1179-1314https://doaj.org/article/5ed92c546ad54a3981e868b4bf323c8f2015-10-01T00:00:00Zhttps://www.dovepress.com/identifying-patients-at-high-risk-of-breast-cancer-recurrence-strategi-peer-reviewed-article-BCTThttps://doaj.org/toc/1179-1314Yehoda M Martei,1 Jennifer M Matro1,21Department of Medicine, Hematology-Oncology Division, 2Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USAAbstract: Identifying patients at high risk of breast cancer recurrence has important implications not only for enabling the ability to provide accurate information to patients but also the potential to improve patient outcomes. Patients at high recurrence risk can be offered appropriate treatment to improve the overall survival. However, the major challenge is identifying patients with early-stage breast cancer at lower risk who may be spared potentially toxic therapy. The successful integration of molecular assays into clinical practice may address the problem of overtreatment and improve overall patient outcomes.Keywords: breast cancer, early stage, genomic assays, recurrence risk, recurrence scoreMartei YMMatro JMDove Medical PressarticleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENBreast Cancer: Targets and Therapy, Vol 2015, Iss default, Pp 337-343 (2015) |
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Martei YM Matro JM Identifying patients at high risk of breast cancer recurrence: strategies to improve patient outcomes |
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Yehoda M Martei,1 Jennifer M Matro1,21Department of Medicine, Hematology-Oncology Division, 2Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USAAbstract: Identifying patients at high risk of breast cancer recurrence has important implications not only for enabling the ability to provide accurate information to patients but also the potential to improve patient outcomes. Patients at high recurrence risk can be offered appropriate treatment to improve the overall survival. However, the major challenge is identifying patients with early-stage breast cancer at lower risk who may be spared potentially toxic therapy. The successful integration of molecular assays into clinical practice may address the problem of overtreatment and improve overall patient outcomes.Keywords: breast cancer, early stage, genomic assays, recurrence risk, recurrence score |
format |
article |
author |
Martei YM Matro JM |
author_facet |
Martei YM Matro JM |
author_sort |
Martei YM |
title |
Identifying patients at high risk of breast cancer recurrence: strategies to improve patient outcomes |
title_short |
Identifying patients at high risk of breast cancer recurrence: strategies to improve patient outcomes |
title_full |
Identifying patients at high risk of breast cancer recurrence: strategies to improve patient outcomes |
title_fullStr |
Identifying patients at high risk of breast cancer recurrence: strategies to improve patient outcomes |
title_full_unstemmed |
Identifying patients at high risk of breast cancer recurrence: strategies to improve patient outcomes |
title_sort |
identifying patients at high risk of breast cancer recurrence: strategies to improve patient outcomes |
publisher |
Dove Medical Press |
publishDate |
2015 |
url |
https://doaj.org/article/5ed92c546ad54a3981e868b4bf323c8f |
work_keys_str_mv |
AT marteiym identifyingpatientsathighriskofbreastcancerrecurrencestrategiestoimprovepatientoutcomes AT matrojm identifyingpatientsathighriskofbreastcancerrecurrencestrategiestoimprovepatientoutcomes |
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