Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment

Rubin et al. introduce transcription factor enrichment analysis (TFEA), a new motif enrichment method specifically aimed at maximizing the informative nature of differential RNA polymerase initiation data. It provides an easy, rigorous, and cost-effective analysis aimed at deciphering the temporal a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jonathan D. Rubin, Jacob T. Stanley, Rutendo F. Sigauke, Cecilia B. Levandowski, Zachary L. Maas, Jessica Westfall, Dylan J. Taatjes, Robin D. Dowell
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Acceso en línea:https://doaj.org/article/5efe066cfacc491fafa057cc4297ed32
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:5efe066cfacc491fafa057cc4297ed32
record_format dspace
spelling oai:doaj.org-article:5efe066cfacc491fafa057cc4297ed322021-12-02T15:02:56ZTranscription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment10.1038/s42003-021-02153-72399-3642https://doaj.org/article/5efe066cfacc491fafa057cc4297ed322021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02153-7https://doaj.org/toc/2399-3642Rubin et al. introduce transcription factor enrichment analysis (TFEA), a new motif enrichment method specifically aimed at maximizing the informative nature of differential RNA polymerase initiation data. It provides an easy, rigorous, and cost-effective analysis aimed at deciphering the temporal and mechanistic details of complex regulatory networks.Jonathan D. RubinJacob T. StanleyRutendo F. SigaukeCecilia B. LevandowskiZachary L. MaasJessica WestfallDylan J. TaatjesRobin D. DowellNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Jonathan D. Rubin
Jacob T. Stanley
Rutendo F. Sigauke
Cecilia B. Levandowski
Zachary L. Maas
Jessica Westfall
Dylan J. Taatjes
Robin D. Dowell
Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment
description Rubin et al. introduce transcription factor enrichment analysis (TFEA), a new motif enrichment method specifically aimed at maximizing the informative nature of differential RNA polymerase initiation data. It provides an easy, rigorous, and cost-effective analysis aimed at deciphering the temporal and mechanistic details of complex regulatory networks.
format article
author Jonathan D. Rubin
Jacob T. Stanley
Rutendo F. Sigauke
Cecilia B. Levandowski
Zachary L. Maas
Jessica Westfall
Dylan J. Taatjes
Robin D. Dowell
author_facet Jonathan D. Rubin
Jacob T. Stanley
Rutendo F. Sigauke
Cecilia B. Levandowski
Zachary L. Maas
Jessica Westfall
Dylan J. Taatjes
Robin D. Dowell
author_sort Jonathan D. Rubin
title Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment
title_short Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment
title_full Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment
title_fullStr Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment
title_full_unstemmed Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment
title_sort transcription factor enrichment analysis (tfea) quantifies the activity of multiple transcription factors from a single experiment
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5efe066cfacc491fafa057cc4297ed32
work_keys_str_mv AT jonathandrubin transcriptionfactorenrichmentanalysistfeaquantifiestheactivityofmultipletranscriptionfactorsfromasingleexperiment
AT jacobtstanley transcriptionfactorenrichmentanalysistfeaquantifiestheactivityofmultipletranscriptionfactorsfromasingleexperiment
AT rutendofsigauke transcriptionfactorenrichmentanalysistfeaquantifiestheactivityofmultipletranscriptionfactorsfromasingleexperiment
AT ceciliablevandowski transcriptionfactorenrichmentanalysistfeaquantifiestheactivityofmultipletranscriptionfactorsfromasingleexperiment
AT zacharylmaas transcriptionfactorenrichmentanalysistfeaquantifiestheactivityofmultipletranscriptionfactorsfromasingleexperiment
AT jessicawestfall transcriptionfactorenrichmentanalysistfeaquantifiestheactivityofmultipletranscriptionfactorsfromasingleexperiment
AT dylanjtaatjes transcriptionfactorenrichmentanalysistfeaquantifiestheactivityofmultipletranscriptionfactorsfromasingleexperiment
AT robinddowell transcriptionfactorenrichmentanalysistfeaquantifiestheactivityofmultipletranscriptionfactorsfromasingleexperiment
_version_ 1718389079663443968