Suicide as an Inflammatory Process: A CRP-based Case-control Study

Introduction:The number of suicide attempts and related deaths among adolescents is increasing every day. Although suicide presents a problem for the general population, it is a more serious problem for those with psychiatric diseases. Previous studies demonstrated the association between inflammati...

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Autores principales:	Gamze Gökalp, Emel Berksoy, Şefika Bardak, Şule Demir, Gülşah Demir, Murat Anıl
Formato:	article
Lenguaje:	EN TR
Publicado:	Galenos Yayinevi 2021
Materias:	suicide inflammation crp Medicine R Pediatrics RJ1-570 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Acceso en línea:	https://doaj.org/article/5efe4226d57c4c119890620cda2ca405
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spelling	oai:doaj.org-article:5efe4226d57c4c119890620cda2ca4052021-11-23T10:20:16ZSuicide as an Inflammatory Process: A CRP-based Case-control Study2146-23992148-733210.4274/cayd.galenos.2021.75437https://doaj.org/article/5efe4226d57c4c119890620cda2ca4052021-12-01T00:00:00Z http://www.caybdergi.com/archives/archive-detail/article-preview/suicide-as-an-nflammatory-process-a-crp-based-case/49679 https://doaj.org/toc/2146-2399https://doaj.org/toc/2148-7332Introduction:The number of suicide attempts and related deaths among adolescents is increasing every day. Although suicide presents a problem for the general population, it is a more serious problem for those with psychiatric diseases. Previous studies demonstrated the association between inflammation and psychiatric disease. Thus, we aim to investigate the relationship between adolescent suicide attempts and the inflammatory biomarker C-reactive protein (CRP).Methods:This research was designed as a case-control study. The study population consisted of patients who been admitted to the pediatric emergency department between 01.03.2016 and 01.03.2019 following a suicide attempt. Healthy volunteers of similar age and gender characteristics who had been admitted to the pediatric clinic for routine examination were also recruited. The groups were compared in terms of demographic and clinical features and serum CRP levels.Results:A total of 239 patients (108 patients and 131 controls) were included in the study. No difference in terms of demographic data was noted between the groups. The serum CRP levels of the control and suicide groups were 1.5±1.5 and 12.7±6.4 mg/L, respectively (p<0.01). The mean serum CRP levels of cases with and without psychiatric disorders were 14.3±4.2 and 9.7±2.7 mg/L, respectively (p=0.03).Conclusion:Levels of CRP, a strong inflammatory marker, were higher in patients who had attempted suicide than in those who had not. CRP levels were also higher in patients with a psychiatric disease than in those without.Gamze GökalpEmel BerksoyŞefika BardakŞule DemirGülşah DemirMurat AnılGalenos YayineviarticlesuicideinflammationcrpMedicineRPediatricsRJ1-570Medical emergencies. Critical care. Intensive care. First aidRC86-88.9ENTRJournal of Pediatric Emergency and Intensive Care Medicine, Vol 8, Iss 3, Pp 166-171 (2021)
institution	DOAJ
collection	DOAJ
language	EN TR
topic	suicide inflammation crp Medicine R Pediatrics RJ1-570 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
spellingShingle	suicide inflammation crp Medicine R Pediatrics RJ1-570 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9 Gamze Gökalp Emel Berksoy Şefika Bardak Şule Demir Gülşah Demir Murat Anıl Suicide as an Inflammatory Process: A CRP-based Case-control Study
description	Introduction:The number of suicide attempts and related deaths among adolescents is increasing every day. Although suicide presents a problem for the general population, it is a more serious problem for those with psychiatric diseases. Previous studies demonstrated the association between inflammation and psychiatric disease. Thus, we aim to investigate the relationship between adolescent suicide attempts and the inflammatory biomarker C-reactive protein (CRP).Methods:This research was designed as a case-control study. The study population consisted of patients who been admitted to the pediatric emergency department between 01.03.2016 and 01.03.2019 following a suicide attempt. Healthy volunteers of similar age and gender characteristics who had been admitted to the pediatric clinic for routine examination were also recruited. The groups were compared in terms of demographic and clinical features and serum CRP levels.Results:A total of 239 patients (108 patients and 131 controls) were included in the study. No difference in terms of demographic data was noted between the groups. The serum CRP levels of the control and suicide groups were 1.5±1.5 and 12.7±6.4 mg/L, respectively (p<0.01). The mean serum CRP levels of cases with and without psychiatric disorders were 14.3±4.2 and 9.7±2.7 mg/L, respectively (p=0.03).Conclusion:Levels of CRP, a strong inflammatory marker, were higher in patients who had attempted suicide than in those who had not. CRP levels were also higher in patients with a psychiatric disease than in those without.
format	article
author	Gamze Gökalp Emel Berksoy Şefika Bardak Şule Demir Gülşah Demir Murat Anıl
author_facet	Gamze Gökalp Emel Berksoy Şefika Bardak Şule Demir Gülşah Demir Murat Anıl
author_sort	Gamze Gökalp
title	Suicide as an Inflammatory Process: A CRP-based Case-control Study
title_short	Suicide as an Inflammatory Process: A CRP-based Case-control Study
title_full	Suicide as an Inflammatory Process: A CRP-based Case-control Study
title_fullStr	Suicide as an Inflammatory Process: A CRP-based Case-control Study
title_full_unstemmed	Suicide as an Inflammatory Process: A CRP-based Case-control Study
title_sort	suicide as an inflammatory process: a crp-based case-control study
publisher	Galenos Yayinevi
publishDate	2021
url	https://doaj.org/article/5efe4226d57c4c119890620cda2ca405
work_keys_str_mv	AT gamzegokalp suicideasaninflammatoryprocessacrpbasedcasecontrolstudy AT emelberksoy suicideasaninflammatoryprocessacrpbasedcasecontrolstudy AT sefikabardak suicideasaninflammatoryprocessacrpbasedcasecontrolstudy AT suledemir suicideasaninflammatoryprocessacrpbasedcasecontrolstudy AT gulsahdemir suicideasaninflammatoryprocessacrpbasedcasecontrolstudy AT muratanıl suicideasaninflammatoryprocessacrpbasedcasecontrolstudy
_version_	1718416766331256832

Suicide as an Inflammatory Process: A CRP-based Case-control Study

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