Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells

Red blood cells, which do not possess a nucleus, have circadian redox rhythms with incompletely understood regulatory mechanisms. Here the authors show that glucose metabolism plays a crucial role in regulating circadian redox status of human red blood cells.

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Autores principales: Ratnasekhar Ch, Guillaume Rey, Sandipan Ray, Pawan K. Jha, Paul C. Driscoll, Mariana Silva Dos Santos, Dania M. Malik, Radoslaw Lach, Aalim M. Weljie, James I. MacRae, Utham K. Valekunja, Akhilesh B. Reddy
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5f02b6e3c1e54ddcb29ebb7ccce4706e
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spelling oai:doaj.org-article:5f02b6e3c1e54ddcb29ebb7ccce4706e2021-12-02T15:22:48ZRhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells10.1038/s41467-020-20479-42041-1723https://doaj.org/article/5f02b6e3c1e54ddcb29ebb7ccce4706e2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20479-4https://doaj.org/toc/2041-1723Red blood cells, which do not possess a nucleus, have circadian redox rhythms with incompletely understood regulatory mechanisms. Here the authors show that glucose metabolism plays a crucial role in regulating circadian redox status of human red blood cells.Ratnasekhar ChGuillaume ReySandipan RayPawan K. JhaPaul C. DriscollMariana Silva Dos SantosDania M. MalikRadoslaw LachAalim M. WeljieJames I. MacRaeUtham K. ValekunjaAkhilesh B. ReddyNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ratnasekhar Ch
Guillaume Rey
Sandipan Ray
Pawan K. Jha
Paul C. Driscoll
Mariana Silva Dos Santos
Dania M. Malik
Radoslaw Lach
Aalim M. Weljie
James I. MacRae
Utham K. Valekunja
Akhilesh B. Reddy
Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells
description Red blood cells, which do not possess a nucleus, have circadian redox rhythms with incompletely understood regulatory mechanisms. Here the authors show that glucose metabolism plays a crucial role in regulating circadian redox status of human red blood cells.
format article
author Ratnasekhar Ch
Guillaume Rey
Sandipan Ray
Pawan K. Jha
Paul C. Driscoll
Mariana Silva Dos Santos
Dania M. Malik
Radoslaw Lach
Aalim M. Weljie
James I. MacRae
Utham K. Valekunja
Akhilesh B. Reddy
author_facet Ratnasekhar Ch
Guillaume Rey
Sandipan Ray
Pawan K. Jha
Paul C. Driscoll
Mariana Silva Dos Santos
Dania M. Malik
Radoslaw Lach
Aalim M. Weljie
James I. MacRae
Utham K. Valekunja
Akhilesh B. Reddy
author_sort Ratnasekhar Ch
title Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells
title_short Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells
title_full Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells
title_fullStr Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells
title_full_unstemmed Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells
title_sort rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5f02b6e3c1e54ddcb29ebb7ccce4706e
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