Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy
The immunosuppressive tumor environment and the lack of functional anti-tumor immunity are major limiting factors in immunotherapy. Here the authors show that human and mouse tumors are infiltrated by virus-specific memory T cells, which can be harnessed by viral peptides to induce local and systemi...
Guardado en:
Autores principales: | Pamela C. Rosato, Sathi Wijeyesinghe, J. Michael Stolley, Christine E. Nelson, Rachel L. Davis, Luke S. Manlove, Christopher A. Pennell, Bruce R. Blazar, Clark C. Chen, Melissa A. Geller, Vaiva Vezys, David Masopust |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5f068cea4ece4349a43cb5cd50da3600 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Repurposing an atherosclerosis targeting peptide for tumor imaging
por: Luciana Kovacs, et al.
Publicado: (2022) -
Targeted Anti‐Tumor Immunotherapy Using Tumor Infiltrating Cells
por: Yifan Xie, et al.
Publicado: (2021) -
Nanomaterial-Based Tumor Photothermal Immunotherapy
por: Xu P, et al.
Publicado: (2020) -
Targeting Tumor-Associated Macrophages in Cancer Immunotherapy
por: Amy J. Petty, et al.
Publicado: (2021) -
Cancer Vaccines and Immunotherapy for Tumor Prevention and Treatment
por: Jagmohan Singh, et al.
Publicado: (2021)