Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation

RNA modifications, including 5-methylcytosines, are known regulators of RNA metabolism affecting protein-RNA binding. Here, the authors reveal the role of m5C in the biogenesis of the non-coding vault-derived small RNAs.

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Autores principales:	Abdulrahim A. Sajini, Nila Roy Choudhury, Rebecca E. Wagner, Susanne Bornelöv, Tommaso Selmi, Christos Spanos, Sabine Dietmann, Juri Rappsilber, Gracjan Michlewski, Michaela Frye
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5f0b467423244eb692f642c3ff84eeee
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spelling	oai:doaj.org-article:5f0b467423244eb692f642c3ff84eeee2021-12-02T14:40:18ZLoss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation10.1038/s41467-019-10020-72041-1723https://doaj.org/article/5f0b467423244eb692f642c3ff84eeee2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10020-7https://doaj.org/toc/2041-1723RNA modifications, including 5-methylcytosines, are known regulators of RNA metabolism affecting protein-RNA binding. Here, the authors reveal the role of m5C in the biogenesis of the non-coding vault-derived small RNAs.Abdulrahim A. SajiniNila Roy ChoudhuryRebecca E. WagnerSusanne BornelövTommaso SelmiChristos SpanosSabine DietmannJuri RappsilberGracjan MichlewskiMichaela FryeNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Abdulrahim A. Sajini Nila Roy Choudhury Rebecca E. Wagner Susanne Bornelöv Tommaso Selmi Christos Spanos Sabine Dietmann Juri Rappsilber Gracjan Michlewski Michaela Frye Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation
description	RNA modifications, including 5-methylcytosines, are known regulators of RNA metabolism affecting protein-RNA binding. Here, the authors reveal the role of m5C in the biogenesis of the non-coding vault-derived small RNAs.
format	article
author	Abdulrahim A. Sajini Nila Roy Choudhury Rebecca E. Wagner Susanne Bornelöv Tommaso Selmi Christos Spanos Sabine Dietmann Juri Rappsilber Gracjan Michlewski Michaela Frye
author_facet	Abdulrahim A. Sajini Nila Roy Choudhury Rebecca E. Wagner Susanne Bornelöv Tommaso Selmi Christos Spanos Sabine Dietmann Juri Rappsilber Gracjan Michlewski Michaela Frye
author_sort	Abdulrahim A. Sajini
title	Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation
title_short	Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation
title_full	Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation
title_fullStr	Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation
title_full_unstemmed	Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation
title_sort	loss of 5-methylcytosine alters the biogenesis of vault-derived small rnas to coordinate epidermal differentiation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/5f0b467423244eb692f642c3ff84eeee
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Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation

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