Pan-cancer analysis reveals cooperativity of both strands of microRNA that regulate tumorigenesis and patient survival

5p and 3p miRNA strands have different mRNA-targeting sequences and may both functionally impact gene expression in cancer. Here, the authors undertake a pan-cancer analysis that indicates 5p/3p miRNA strands function together to regulate tumorigenic processes.

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Autores principales: Ramkrishna Mitra, Clare M. Adams, Wei Jiang, Evan Greenawalt, Christine M. Eischen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/5f0e591b78494b16971cad334299541c
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