I1 imidazoline receptor: novel potential cytoprotective target of TVP1022, the S-enantiomer of rasagiline.
TVP1022, the S-enantiomer of rasagiline (Azilect®) (N-propargyl-1R-aminoindan), exerts cyto/cardio-protective effects in a variety of experimental cardiac and neuronal models. Previous studies have demonstrated that the protective activity of TVP1022 and other propargyl derivatives involve the activ...
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Main Authors: | Yaron D Barac, Orit Bar-Am, Esti Liani, Tamar Amit, Luba Frolov, Elena Ovcharenko, Itzchak Angel, Moussa B H Youdim, Ofer Binah |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/5f118b38e1ff4e3085d81f99839f6506 |
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