Influence of chronic alcoholic intoxication and lighting regime on karyometric and ploidometric parameters of hepatocytes of rats
The features of the diurnal dynamics of the area of rat hepatocyte nuclei and their ploidy were studied under conditions of a standart (fixed) light regime and constant illumination, as well as under chronic exposure to alcohol in the mentioned light regimes. It has been shown that exposure to alco...
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Firenze University Press
2021
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oai:doaj.org-article:5f138f503c524135bd3d7e0b03ddfbc62021-11-28T20:31:40ZInfluence of chronic alcoholic intoxication and lighting regime on karyometric and ploidometric parameters of hepatocytes of rats0008-71142165-5391https://doaj.org/article/5f138f503c524135bd3d7e0b03ddfbc62021-11-01T00:00:00Zhttps://riviste.fupress.net/index.php/caryologia/article/view/1122https://doaj.org/toc/0008-7114https://doaj.org/toc/2165-5391 The features of the diurnal dynamics of the area of rat hepatocyte nuclei and their ploidy were studied under conditions of a standart (fixed) light regime and constant illumination, as well as under chronic exposure to alcohol in the mentioned light regimes. It has been shown that exposure to alcohol and exposure to constant illumination separately lead to a change in the amplitude-phase characteristics of the circadian rhythm of the nucleus area, while the combined effect of these factors leads to a complete destruction of the rhythm, which indicates a violation of adaptation processes. An increase in the average ploidy of hepatocyte nuclei in chronic alcohol intoxication is also shown, while in animals kept under constant illumination without drinking alcohol, the values of this parameter decrease, which indicates a successful course of the adaptation process. The conducted research indicates that the results of karyometric and ploidometric analysis characterize the degree of influence of alcohol intoxication and changes in the light regime on the liver of rats, reflecting the rate of efficiency of adaptation to these factors. David AreshidzeYuri KirillovLyudmila MakartsevaMaria KozlovaIgor ChernovEvgeniya ShtemplevskayaFirenze University PressarticleBiology (General)QH301-705.5CytologyQH573-671ENCaryologia (2021) |
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DOAJ |
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EN |
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Biology (General) QH301-705.5 Cytology QH573-671 |
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Biology (General) QH301-705.5 Cytology QH573-671 David Areshidze Yuri Kirillov Lyudmila Makartseva Maria Kozlova Igor Chernov Evgeniya Shtemplevskaya Influence of chronic alcoholic intoxication and lighting regime on karyometric and ploidometric parameters of hepatocytes of rats |
| description |
The features of the diurnal dynamics of the area of rat hepatocyte nuclei and their ploidy were studied under conditions of a standart (fixed) light regime and constant illumination, as well as under chronic exposure to alcohol in the mentioned light regimes. It has been shown that exposure to alcohol and exposure to constant illumination separately lead to a change in the amplitude-phase characteristics of the circadian rhythm of the nucleus area, while the combined effect of these factors leads to a complete destruction of the rhythm, which indicates a violation of adaptation processes. An increase in the average ploidy of hepatocyte nuclei in chronic alcohol intoxication is also shown, while in animals kept under constant illumination without drinking alcohol, the values of this parameter decrease, which indicates a successful course of the adaptation process. The conducted research indicates that the results of karyometric and ploidometric analysis characterize the degree of influence of alcohol intoxication and changes in the light regime on the liver of rats, reflecting the rate of efficiency of adaptation to these factors.
|
| format |
article |
| author |
David Areshidze Yuri Kirillov Lyudmila Makartseva Maria Kozlova Igor Chernov Evgeniya Shtemplevskaya |
| author_facet |
David Areshidze Yuri Kirillov Lyudmila Makartseva Maria Kozlova Igor Chernov Evgeniya Shtemplevskaya |
| author_sort |
David Areshidze |
| title |
Influence of chronic alcoholic intoxication and lighting regime on karyometric and ploidometric parameters of hepatocytes of rats |
| title_short |
Influence of chronic alcoholic intoxication and lighting regime on karyometric and ploidometric parameters of hepatocytes of rats |
| title_full |
Influence of chronic alcoholic intoxication and lighting regime on karyometric and ploidometric parameters of hepatocytes of rats |
| title_fullStr |
Influence of chronic alcoholic intoxication and lighting regime on karyometric and ploidometric parameters of hepatocytes of rats |
| title_full_unstemmed |
Influence of chronic alcoholic intoxication and lighting regime on karyometric and ploidometric parameters of hepatocytes of rats |
| title_sort |
influence of chronic alcoholic intoxication and lighting regime on karyometric and ploidometric parameters of hepatocytes of rats |
| publisher |
Firenze University Press |
| publishDate |
2021 |
| url |
https://doaj.org/article/5f138f503c524135bd3d7e0b03ddfbc6 |
| work_keys_str_mv |
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1718407770593558528 |