Molecular determinants for the strictly compartmentalized expression of kainate receptors in CA3 pyramidal cells

Kainate receptors are selectively found at CA3-mossy fibre synapses, although the mechanisms regulating this compartmentalisation have yet to be determined. Here, the authors find KAR segregation is dependent on the amount of GluK2a protein and an interaction between the GluK2 C-terminal domain and...

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Autores principales:	Sabine Fièvre, Mario Carta, Ingrid Chamma, Virginie Labrousse, Olivier Thoumine, Christophe Mulle
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5f17c5df5f1f4d16b53ec3e6fb624789
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spelling	oai:doaj.org-article:5f17c5df5f1f4d16b53ec3e6fb6247892021-12-02T15:35:45ZMolecular determinants for the strictly compartmentalized expression of kainate receptors in CA3 pyramidal cells10.1038/ncomms127382041-1723https://doaj.org/article/5f17c5df5f1f4d16b53ec3e6fb6247892016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12738https://doaj.org/toc/2041-1723Kainate receptors are selectively found at CA3-mossy fibre synapses, although the mechanisms regulating this compartmentalisation have yet to be determined. Here, the authors find KAR segregation is dependent on the amount of GluK2a protein and an interaction between the GluK2 C-terminal domain and N-cadherin.Sabine FièvreMario CartaIngrid ChammaVirginie LabrousseOlivier ThoumineChristophe MulleNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sabine Fièvre Mario Carta Ingrid Chamma Virginie Labrousse Olivier Thoumine Christophe Mulle Molecular determinants for the strictly compartmentalized expression of kainate receptors in CA3 pyramidal cells
description	Kainate receptors are selectively found at CA3-mossy fibre synapses, although the mechanisms regulating this compartmentalisation have yet to be determined. Here, the authors find KAR segregation is dependent on the amount of GluK2a protein and an interaction between the GluK2 C-terminal domain and N-cadherin.
format	article
author	Sabine Fièvre Mario Carta Ingrid Chamma Virginie Labrousse Olivier Thoumine Christophe Mulle
author_facet	Sabine Fièvre Mario Carta Ingrid Chamma Virginie Labrousse Olivier Thoumine Christophe Mulle
author_sort	Sabine Fièvre
title	Molecular determinants for the strictly compartmentalized expression of kainate receptors in CA3 pyramidal cells
title_short	Molecular determinants for the strictly compartmentalized expression of kainate receptors in CA3 pyramidal cells
title_full	Molecular determinants for the strictly compartmentalized expression of kainate receptors in CA3 pyramidal cells
title_fullStr	Molecular determinants for the strictly compartmentalized expression of kainate receptors in CA3 pyramidal cells
title_full_unstemmed	Molecular determinants for the strictly compartmentalized expression of kainate receptors in CA3 pyramidal cells
title_sort	molecular determinants for the strictly compartmentalized expression of kainate receptors in ca3 pyramidal cells
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/5f17c5df5f1f4d16b53ec3e6fb624789
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Molecular determinants for the strictly compartmentalized expression of kainate receptors in CA3 pyramidal cells

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