Quinolone Resistance Reversion by Targeting the SOS Response

ABSTRACT Suppression of the SOS response has been postulated as a therapeutic strategy for potentiating antimicrobial agents. We aimed to evaluate the impact of its suppression on reversing resistance using a model of isogenic strains of Escherichia coli representing multiple levels of quinolone res...

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Main Authors: E. Recacha, J. Machuca, P. Díaz de Alba, M. Ramos-Güelfo, F. Docobo-Pérez, J. Rodriguez-Beltrán, J. Blázquez, A. Pascual, J. M. Rodríguez-Martínez
Format: article
Language:EN
Published: American Society for Microbiology 2017
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Online Access:https://doaj.org/article/5f3554f2bb204dd1bdd6df4557674b5d
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