Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis
3-Hydroxypropionic acid (3HP) is an important platform chemical. Here, the authors engineer Halomonas bluephagenesis by deleting newly identified degradation pathway and balancing redox state to achieve high level production of 3HP and its copolymer under open and unsterile conditions.
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Nature Portfolio
2021
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oai:doaj.org-article:5f395d3b472a41b98fa7785ae6cbdc622021-12-02T13:15:00ZHyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis10.1038/s41467-021-21632-32041-1723https://doaj.org/article/5f395d3b472a41b98fa7785ae6cbdc622021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21632-3https://doaj.org/toc/2041-17233-Hydroxypropionic acid (3HP) is an important platform chemical. Here, the authors engineer Halomonas bluephagenesis by deleting newly identified degradation pathway and balancing redox state to achieve high level production of 3HP and its copolymer under open and unsterile conditions.Xiao-Ran JiangXu YanLin-Ping YuXin-Yi LiuGuo-Qiang ChenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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Science Q Xiao-Ran Jiang Xu Yan Lin-Ping Yu Xin-Yi Liu Guo-Qiang Chen Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis |
description |
3-Hydroxypropionic acid (3HP) is an important platform chemical. Here, the authors engineer Halomonas bluephagenesis by deleting newly identified degradation pathway and balancing redox state to achieve high level production of 3HP and its copolymer under open and unsterile conditions. |
format |
article |
author |
Xiao-Ran Jiang Xu Yan Lin-Ping Yu Xin-Yi Liu Guo-Qiang Chen |
author_facet |
Xiao-Ran Jiang Xu Yan Lin-Ping Yu Xin-Yi Liu Guo-Qiang Chen |
author_sort |
Xiao-Ran Jiang |
title |
Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis |
title_short |
Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis |
title_full |
Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis |
title_fullStr |
Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis |
title_full_unstemmed |
Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis |
title_sort |
hyperproduction of 3-hydroxypropionate by halomonas bluephagenesis |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/5f395d3b472a41b98fa7785ae6cbdc62 |
work_keys_str_mv |
AT xiaoranjiang hyperproductionof3hydroxypropionatebyhalomonasbluephagenesis AT xuyan hyperproductionof3hydroxypropionatebyhalomonasbluephagenesis AT linpingyu hyperproductionof3hydroxypropionatebyhalomonasbluephagenesis AT xinyiliu hyperproductionof3hydroxypropionatebyhalomonasbluephagenesis AT guoqiangchen hyperproductionof3hydroxypropionatebyhalomonasbluephagenesis |
_version_ |
1718393387931926528 |