Image contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy

Metal-based nanoparticles (NPs) have been extensively studied for dose enhancement applications in radiation therapy. This study investigated the utility of such NPs for image-guided radiation therapy (IGRT). Phantom images of gold NPs (AuNPs) and titanium peroxide NPs (TiOxNPs) with different conce...

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Autores principales:	Masao Nakayama, Hiroaki Akasaka, Eiichi Miyazaki, Yoshihiro Goto, Yuya Oki, Yosuke Kawate, Kenta Morita, Ryohei Sasaki
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Nanoparticles IGRT Titanium peroxide Theranostics Medical physics. Medical radiology. Nuclear medicine R895-920 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/5f3b2dab33b6420f97e9960b260520ff
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id	oai:doaj.org-article:5f3b2dab33b6420f97e9960b260520ff
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spelling	oai:doaj.org-article:5f3b2dab33b6420f97e9960b260520ff2021-11-24T04:32:28ZImage contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy2405-631610.1016/j.phro.2021.11.003https://doaj.org/article/5f3b2dab33b6420f97e9960b260520ff2021-10-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2405631621000671https://doaj.org/toc/2405-6316Metal-based nanoparticles (NPs) have been extensively studied for dose enhancement applications in radiation therapy. This study investigated the utility of such NPs for image-guided radiation therapy (IGRT). Phantom images of gold NPs (AuNPs) and titanium peroxide NPs (TiOxNPs) with different concentrations were acquired using IGRT modalities, including cone-beam computed tomography (CBCT). AuNPs induced strong contrast enhancement in kV energy CBCT images, whereas TiOxNPs at high concentrations showed weak but detectable changes. The results indicated that these NPs can be used to enhance IGRT images as well as dose enhancement for treatment purposes.Masao NakayamaHiroaki AkasakaEiichi MiyazakiYoshihiro GotoYuya OkiYosuke KawateKenta MoritaRyohei SasakiElsevierarticleNanoparticlesIGRTTitanium peroxideTheranosticsMedical physics. Medical radiology. Nuclear medicineR895-920Neoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENPhysics and Imaging in Radiation Oncology, Vol 20, Iss , Pp 94-97 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Nanoparticles IGRT Titanium peroxide Theranostics Medical physics. Medical radiology. Nuclear medicine R895-920 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Nanoparticles IGRT Titanium peroxide Theranostics Medical physics. Medical radiology. Nuclear medicine R895-920 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Masao Nakayama Hiroaki Akasaka Eiichi Miyazaki Yoshihiro Goto Yuya Oki Yosuke Kawate Kenta Morita Ryohei Sasaki Image contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy
description	Metal-based nanoparticles (NPs) have been extensively studied for dose enhancement applications in radiation therapy. This study investigated the utility of such NPs for image-guided radiation therapy (IGRT). Phantom images of gold NPs (AuNPs) and titanium peroxide NPs (TiOxNPs) with different concentrations were acquired using IGRT modalities, including cone-beam computed tomography (CBCT). AuNPs induced strong contrast enhancement in kV energy CBCT images, whereas TiOxNPs at high concentrations showed weak but detectable changes. The results indicated that these NPs can be used to enhance IGRT images as well as dose enhancement for treatment purposes.
format	article
author	Masao Nakayama Hiroaki Akasaka Eiichi Miyazaki Yoshihiro Goto Yuya Oki Yosuke Kawate Kenta Morita Ryohei Sasaki
author_facet	Masao Nakayama Hiroaki Akasaka Eiichi Miyazaki Yoshihiro Goto Yuya Oki Yosuke Kawate Kenta Morita Ryohei Sasaki
author_sort	Masao Nakayama
title	Image contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy
title_short	Image contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy
title_full	Image contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy
title_fullStr	Image contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy
title_full_unstemmed	Image contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy
title_sort	image contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/5f3b2dab33b6420f97e9960b260520ff
work_keys_str_mv	AT masaonakayama imagecontrastassessmentofmetalbasednanoparticlesasapplicationsforimageguidedradiationtherapy AT hiroakiakasaka imagecontrastassessmentofmetalbasednanoparticlesasapplicationsforimageguidedradiationtherapy AT eiichimiyazaki imagecontrastassessmentofmetalbasednanoparticlesasapplicationsforimageguidedradiationtherapy AT yoshihirogoto imagecontrastassessmentofmetalbasednanoparticlesasapplicationsforimageguidedradiationtherapy AT yuyaoki imagecontrastassessmentofmetalbasednanoparticlesasapplicationsforimageguidedradiationtherapy AT yosukekawate imagecontrastassessmentofmetalbasednanoparticlesasapplicationsforimageguidedradiationtherapy AT kentamorita imagecontrastassessmentofmetalbasednanoparticlesasapplicationsforimageguidedradiationtherapy AT ryoheisasaki imagecontrastassessmentofmetalbasednanoparticlesasapplicationsforimageguidedradiationtherapy
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Image contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy

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