GnRHa protects the ovarian reserve by reducing endoplasmic reticulum stress during cyclophosphamide-based chemotherapy

Abstract Chemotherapy-induced ovarian dysfunction is a serious adverse effect in premenopausal patients with cancer. Gonadotrophin-releasing hormone analogs (GnRHa) protect ovarian function, but its molecular mechanisms have not yet been determined. In this study, we attempted to determine the previ...

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Bibliographic Details
Main Authors: Xiaolin Li, Sixuan Liu, Xuan Chen, Run Huang, Lisi Ma, Huaiyu Weng, Yang Yu, Xiangyun Zong
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/5f42003b8ee944e89ba1d69d78f71cb5
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