Loss of succinyl-CoA synthase ADP-forming β subunit disrupts mtDNA stability and mitochondrial dynamics in neurons
Abstract Succinyl Coenzyme A synthetase (SCS) is a key mitochondrial enzyme. Defected SCS ADP-forming β subunit (SCS A-β) is linked to lethal infantile Leigh or leigh-like syndrome. However, the impacts of SCS A-β deficiency on mitochondria specifically in neurons have not yet been comprehensively i...
Guardado en:
Autores principales: | Yujun Zhao, Jing Tian, Shaomei Sui, Xiaodong Yuan, Hao Chen, Chuanqiang Qu, Yifeng Du, Lan Guo, Heng Du |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5f4d68f35beb4d518f4f69fc1f40df70 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Origins and evolution of the Etruscans' mtDNA.
por: Silvia Ghirotto, et al.
Publicado: (2013) -
mtDNA in the Pathogenesis of Cardiovascular Diseases
por: Lili Wang, et al.
Publicado: (2021) -
Molecular Mechanisms of mtDNA-Mediated Inflammation
por: Anna De Gaetano, et al.
Publicado: (2021) -
Coevolution of Drosophila melanogaster mtDNA and Wolbachia genotypes.
por: Yury Ilinsky
Publicado: (2013) -
Clinical variability and outcome of succinyl‐CoA:3‐ketoacid CoA transferase deficiency caused by a single OXCT1 mutation: Report of 17 cases
por: Malak A. Alghamdi, et al.
Publicado: (2021)