IRF3 Knockout Results in Partial or Complete Rejection of Murine Mesothelioma
Background: Malignant pleural mesothelioma (MESO) has a poor prognosis despite aggressive treatment with surgery, radiation and chemotherapy, and novel therapeutic approaches are needed. IRF3 is a downstream molecule of the cGAS/STING signaling pathway, but its roles have not been investigated in ME...
Guardado en:
Autores principales: | Masaya Aoki, Licun Wu, Junichi Murakami, Yidan Zhao, Hana Yun, Marc de Perrot |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/5f605b1bd0c94dbb8682ab437b585836 |
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