IRF3 Knockout Results in Partial or Complete Rejection of Murine Mesothelioma
Background: Malignant pleural mesothelioma (MESO) has a poor prognosis despite aggressive treatment with surgery, radiation and chemotherapy, and novel therapeutic approaches are needed. IRF3 is a downstream molecule of the cGAS/STING signaling pathway, but its roles have not been investigated in ME...
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Main Authors: | Masaya Aoki, Licun Wu, Junichi Murakami, Yidan Zhao, Hana Yun, Marc de Perrot |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Subjects: | |
Online Access: | https://doaj.org/article/5f605b1bd0c94dbb8682ab437b585836 |
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