IRF3 Knockout Results in Partial or Complete Rejection of Murine Mesothelioma

Background: Malignant pleural mesothelioma (MESO) has a poor prognosis despite aggressive treatment with surgery, radiation and chemotherapy, and novel therapeutic approaches are needed. IRF3 is a downstream molecule of the cGAS/STING signaling pathway, but its roles have not been investigated in ME...

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Autores principales: Masaya Aoki, Licun Wu, Junichi Murakami, Yidan Zhao, Hana Yun, Marc de Perrot
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/5f605b1bd0c94dbb8682ab437b585836
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