Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2

RNA polymerase II needs to be imported into the nucleus to perform transcription. Fianu et al. show that RPAP2 binds to Pol II and enters the nucleus with it, before releasing it to perform transcription and returning to the cytoplasm.

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Auteurs principaux: Isaac Fianu, Christian Dienemann, Shintaro Aibara, Sandra Schilbach, Patrick Cramer
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/5f61211da5b646c69952d51767e5f8fe
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