Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2

Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2

RNA polymerase II needs to be imported into the nucleus to perform transcription. Fianu et al. show that RPAP2 binds to Pol II and enters the nucleus with it, before releasing it to perform transcription and returning to the cytoplasm.

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Detalles Bibliográficos
Autores principales: Isaac Fianu, Christian Dienemann, Shintaro Aibara, Sandra Schilbach, Patrick Cramer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/5f61211da5b646c69952d51767e5f8fe
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