Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing

Many proteins which sense membrane curvature contain intrinsically disordered domains. Here the authors use Monte Carlo simulations combined with experimental approaches and report that disordered domains are potent sensors of membrane curvature.

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Auteurs principaux:	Wade F. Zeno, Upayan Baul, Wilton T. Snead, Andre C. M. DeGroot, Liping Wang, Eileen M. Lafer, D. Thirumalai, Jeanne C. Stachowiak
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2018
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/5f61987e274540b184a22aa18a68b20c
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spelling	oai:doaj.org-article:5f61987e274540b184a22aa18a68b20c2021-12-02T15:34:43ZSynergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing10.1038/s41467-018-06532-32041-1723https://doaj.org/article/5f61987e274540b184a22aa18a68b20c2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06532-3https://doaj.org/toc/2041-1723Many proteins which sense membrane curvature contain intrinsically disordered domains. Here the authors use Monte Carlo simulations combined with experimental approaches and report that disordered domains are potent sensors of membrane curvature.Wade F. ZenoUpayan BaulWilton T. SneadAndre C. M. DeGrootLiping WangEileen M. LaferD. ThirumalaiJeanne C. StachowiakNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wade F. Zeno Upayan Baul Wilton T. Snead Andre C. M. DeGroot Liping Wang Eileen M. Lafer D. Thirumalai Jeanne C. Stachowiak Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
description	Many proteins which sense membrane curvature contain intrinsically disordered domains. Here the authors use Monte Carlo simulations combined with experimental approaches and report that disordered domains are potent sensors of membrane curvature.
format	article
author	Wade F. Zeno Upayan Baul Wilton T. Snead Andre C. M. DeGroot Liping Wang Eileen M. Lafer D. Thirumalai Jeanne C. Stachowiak
author_facet	Wade F. Zeno Upayan Baul Wilton T. Snead Andre C. M. DeGroot Liping Wang Eileen M. Lafer D. Thirumalai Jeanne C. Stachowiak
author_sort	Wade F. Zeno
title	Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
title_short	Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
title_full	Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
title_fullStr	Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
title_full_unstemmed	Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
title_sort	synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/5f61987e274540b184a22aa18a68b20c
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_version_	1718386782896128000

Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing

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