Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing

Many proteins which sense membrane curvature contain intrinsically disordered domains. Here the authors use Monte Carlo simulations combined with experimental approaches and report that disordered domains are potent sensors of membrane curvature.

Guardado en:

Detalles Bibliográficos
Autores principales:	Wade F. Zeno, Upayan Baul, Wilton T. Snead, Andre C. M. DeGroot, Liping Wang, Eileen M. Lafer, D. Thirumalai, Jeanne C. Stachowiak
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5f61987e274540b184a22aa18a68b20c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5f61987e274540b184a22aa18a68b20c
record_format	dspace
spelling	oai:doaj.org-article:5f61987e274540b184a22aa18a68b20c2021-12-02T15:34:43ZSynergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing10.1038/s41467-018-06532-32041-1723https://doaj.org/article/5f61987e274540b184a22aa18a68b20c2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06532-3https://doaj.org/toc/2041-1723Many proteins which sense membrane curvature contain intrinsically disordered domains. Here the authors use Monte Carlo simulations combined with experimental approaches and report that disordered domains are potent sensors of membrane curvature.Wade F. ZenoUpayan BaulWilton T. SneadAndre C. M. DeGrootLiping WangEileen M. LaferD. ThirumalaiJeanne C. StachowiakNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wade F. Zeno Upayan Baul Wilton T. Snead Andre C. M. DeGroot Liping Wang Eileen M. Lafer D. Thirumalai Jeanne C. Stachowiak Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
description	Many proteins which sense membrane curvature contain intrinsically disordered domains. Here the authors use Monte Carlo simulations combined with experimental approaches and report that disordered domains are potent sensors of membrane curvature.
format	article
author	Wade F. Zeno Upayan Baul Wilton T. Snead Andre C. M. DeGroot Liping Wang Eileen M. Lafer D. Thirumalai Jeanne C. Stachowiak
author_facet	Wade F. Zeno Upayan Baul Wilton T. Snead Andre C. M. DeGroot Liping Wang Eileen M. Lafer D. Thirumalai Jeanne C. Stachowiak
author_sort	Wade F. Zeno
title	Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
title_short	Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
title_full	Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
title_fullStr	Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
title_full_unstemmed	Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
title_sort	synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/5f61987e274540b184a22aa18a68b20c
work_keys_str_mv	AT wadefzeno synergybetweenintrinsicallydisordereddomainsandstructuredproteinsamplifiesmembranecurvaturesensing AT upayanbaul synergybetweenintrinsicallydisordereddomainsandstructuredproteinsamplifiesmembranecurvaturesensing AT wiltontsnead synergybetweenintrinsicallydisordereddomainsandstructuredproteinsamplifiesmembranecurvaturesensing AT andrecmdegroot synergybetweenintrinsicallydisordereddomainsandstructuredproteinsamplifiesmembranecurvaturesensing AT lipingwang synergybetweenintrinsicallydisordereddomainsandstructuredproteinsamplifiesmembranecurvaturesensing AT eileenmlafer synergybetweenintrinsicallydisordereddomainsandstructuredproteinsamplifiesmembranecurvaturesensing AT dthirumalai synergybetweenintrinsicallydisordereddomainsandstructuredproteinsamplifiesmembranecurvaturesensing AT jeannecstachowiak synergybetweenintrinsicallydisordereddomainsandstructuredproteinsamplifiesmembranecurvaturesensing
_version_	1718386782896128000

Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing

Ejemplares similares