Freeze–thaw characterization process to minimize aggregation and enable drug product manufacturing of protein based therapeutics
Abstract Physical instabilities of proteins in the form of protein aggregation continue to be a major challenge in the development of protein drug candidates. Aggregation can occur during different stages of product lifecycle such as freeze–thaw, manufacturing, shipping, and storage, and can potenti...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
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Nature Portfolio
2021
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| Accès en ligne: | https://doaj.org/article/5f6a093b2b524b8da2bed8f3f6f2e893 |
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