Structure and function of the Zika virus full-length NS5 protein
Zika virus infection can cause human birth defects and Guillain-Barré syndrome. Here the authors present the structures of the full-length nonstructural protein 5 and its RNA-dependent RNA polymerase domain of Zika virus, which are targets for inhibitors of virus replication.
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Nature Portfolio
2017
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oai:doaj.org-article:5f7cf37477dd4b07ab2f1f59b91eee8b2021-12-02T14:40:37ZStructure and function of the Zika virus full-length NS5 protein10.1038/ncomms147622041-1723https://doaj.org/article/5f7cf37477dd4b07ab2f1f59b91eee8b2017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14762https://doaj.org/toc/2041-1723Zika virus infection can cause human birth defects and Guillain-Barré syndrome. Here the authors present the structures of the full-length nonstructural protein 5 and its RNA-dependent RNA polymerase domain of Zika virus, which are targets for inhibitors of virus replication.Baoyu ZhaoGuanghui YiFenglei DuYin-Chih ChuangRobert C. VaughanBanumathi SankaranC. Cheng KaoPingwei LiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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Science Q Baoyu Zhao Guanghui Yi Fenglei Du Yin-Chih Chuang Robert C. Vaughan Banumathi Sankaran C. Cheng Kao Pingwei Li Structure and function of the Zika virus full-length NS5 protein |
description |
Zika virus infection can cause human birth defects and Guillain-Barré syndrome. Here the authors present the structures of the full-length nonstructural protein 5 and its RNA-dependent RNA polymerase domain of Zika virus, which are targets for inhibitors of virus replication. |
format |
article |
author |
Baoyu Zhao Guanghui Yi Fenglei Du Yin-Chih Chuang Robert C. Vaughan Banumathi Sankaran C. Cheng Kao Pingwei Li |
author_facet |
Baoyu Zhao Guanghui Yi Fenglei Du Yin-Chih Chuang Robert C. Vaughan Banumathi Sankaran C. Cheng Kao Pingwei Li |
author_sort |
Baoyu Zhao |
title |
Structure and function of the Zika virus full-length NS5 protein |
title_short |
Structure and function of the Zika virus full-length NS5 protein |
title_full |
Structure and function of the Zika virus full-length NS5 protein |
title_fullStr |
Structure and function of the Zika virus full-length NS5 protein |
title_full_unstemmed |
Structure and function of the Zika virus full-length NS5 protein |
title_sort |
structure and function of the zika virus full-length ns5 protein |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/5f7cf37477dd4b07ab2f1f59b91eee8b |
work_keys_str_mv |
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1718390239842533376 |