Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis
Yeast exhibit oscillations that share features with circadian rhythms. The authors show that bioenergetic constraints promote oscillatory behaviour: resources are stored until supplies can support translational bursting, this is licensed by ion transport and release from membrane-less compartments.
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Nature Portfolio
2020
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oai:doaj.org-article:5f80bcd8c3434476af92702098c2e29a2021-12-02T18:02:32ZEukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis10.1038/s41467-020-18330-x2041-1723https://doaj.org/article/5f80bcd8c3434476af92702098c2e29a2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18330-xhttps://doaj.org/toc/2041-1723Yeast exhibit oscillations that share features with circadian rhythms. The authors show that bioenergetic constraints promote oscillatory behaviour: resources are stored until supplies can support translational bursting, this is licensed by ion transport and release from membrane-less compartments.John S. O’ NeillNathaniel P. HoyleJ. Brian RobertsonRachel S. EdgarAndrew D. BealeSew Y. Peak-ChewJason DayAna S. H. CostaChristian FrezzaHelen C. CaustonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q John S. O’ Neill Nathaniel P. Hoyle J. Brian Robertson Rachel S. Edgar Andrew D. Beale Sew Y. Peak-Chew Jason Day Ana S. H. Costa Christian Frezza Helen C. Causton Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis |
description |
Yeast exhibit oscillations that share features with circadian rhythms. The authors show that bioenergetic constraints promote oscillatory behaviour: resources are stored until supplies can support translational bursting, this is licensed by ion transport and release from membrane-less compartments. |
format |
article |
author |
John S. O’ Neill Nathaniel P. Hoyle J. Brian Robertson Rachel S. Edgar Andrew D. Beale Sew Y. Peak-Chew Jason Day Ana S. H. Costa Christian Frezza Helen C. Causton |
author_facet |
John S. O’ Neill Nathaniel P. Hoyle J. Brian Robertson Rachel S. Edgar Andrew D. Beale Sew Y. Peak-Chew Jason Day Ana S. H. Costa Christian Frezza Helen C. Causton |
author_sort |
John S. O’ Neill |
title |
Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis |
title_short |
Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis |
title_full |
Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis |
title_fullStr |
Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis |
title_full_unstemmed |
Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis |
title_sort |
eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/5f80bcd8c3434476af92702098c2e29a |
work_keys_str_mv |
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1718378869558345728 |