Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis

Yeast exhibit oscillations that share features with circadian rhythms. The authors show that bioenergetic constraints promote oscillatory behaviour: resources are stored until supplies can support translational bursting, this is licensed by ion transport and release from membrane-less compartments.

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Autores principales: John S. O’ Neill, Nathaniel P. Hoyle, J. Brian Robertson, Rachel S. Edgar, Andrew D. Beale, Sew Y. Peak-Chew, Jason Day, Ana S. H. Costa, Christian Frezza, Helen C. Causton
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/5f80bcd8c3434476af92702098c2e29a
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spelling oai:doaj.org-article:5f80bcd8c3434476af92702098c2e29a2021-12-02T18:02:32ZEukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis10.1038/s41467-020-18330-x2041-1723https://doaj.org/article/5f80bcd8c3434476af92702098c2e29a2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18330-xhttps://doaj.org/toc/2041-1723Yeast exhibit oscillations that share features with circadian rhythms. The authors show that bioenergetic constraints promote oscillatory behaviour: resources are stored until supplies can support translational bursting, this is licensed by ion transport and release from membrane-less compartments.John S. O’ NeillNathaniel P. HoyleJ. Brian RobertsonRachel S. EdgarAndrew D. BealeSew Y. Peak-ChewJason DayAna S. H. CostaChristian FrezzaHelen C. CaustonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
John S. O’ Neill
Nathaniel P. Hoyle
J. Brian Robertson
Rachel S. Edgar
Andrew D. Beale
Sew Y. Peak-Chew
Jason Day
Ana S. H. Costa
Christian Frezza
Helen C. Causton
Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis
description Yeast exhibit oscillations that share features with circadian rhythms. The authors show that bioenergetic constraints promote oscillatory behaviour: resources are stored until supplies can support translational bursting, this is licensed by ion transport and release from membrane-less compartments.
format article
author John S. O’ Neill
Nathaniel P. Hoyle
J. Brian Robertson
Rachel S. Edgar
Andrew D. Beale
Sew Y. Peak-Chew
Jason Day
Ana S. H. Costa
Christian Frezza
Helen C. Causton
author_facet John S. O’ Neill
Nathaniel P. Hoyle
J. Brian Robertson
Rachel S. Edgar
Andrew D. Beale
Sew Y. Peak-Chew
Jason Day
Ana S. H. Costa
Christian Frezza
Helen C. Causton
author_sort John S. O’ Neill
title Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis
title_short Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis
title_full Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis
title_fullStr Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis
title_full_unstemmed Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis
title_sort eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/5f80bcd8c3434476af92702098c2e29a
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