The Effect of Sociodemographic Factors, Parity and Cervical Cancer on Antibiotic Treatment for Uncomplicated Cystitis in Women: A Nationwide Cohort Study

Background: Uncomplicated cystitis is one of the most common reasons for antibiotic treatment in otherwise healthy women. Nationwide studies on antibiotic treatment for this infection and in relation to factors beyond the infection itself have hitherto not been available. Methods: This was a nationw...

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Autores principales:	Filip Jansåker, Xinjun Li, Jenny Dahl Knudsen, Veronica Milos Nymberg, Kristina Sundquist
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	antibiotics cervical cancer cystitis parity sociodemographic factors UTI Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/5f8268b3c9ac4b75b9a494109f4adbd7
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spelling	oai:doaj.org-article:5f8268b3c9ac4b75b9a494109f4adbd72021-11-25T16:24:31ZThe Effect of Sociodemographic Factors, Parity and Cervical Cancer on Antibiotic Treatment for Uncomplicated Cystitis in Women: A Nationwide Cohort Study10.3390/antibiotics101113892079-6382https://doaj.org/article/5f8268b3c9ac4b75b9a494109f4adbd72021-11-01T00:00:00Zhttps://www.mdpi.com/2079-6382/10/11/1389https://doaj.org/toc/2079-6382Background: Uncomplicated cystitis is one of the most common reasons for antibiotic treatment in otherwise healthy women. Nationwide studies on antibiotic treatment for this infection and in relation to factors beyond the infection itself have hitherto not been available. Methods: This was a nationwide open cohort study consisting of 352,507 women aged 15–50 years with uncomplicated cystitis (2006–2018). The outcome was a redeemed antibiotic prescription within five days from the cystitis diagnosis. Logistic regression models were used to examine the relationship between the outcome and the predictor variables. Results: This study identified 192,065 redeemed treatments (54.5%). Several sociodemographic variables were associated with antibiotic treatment. For example, women with the lowest income had an odds ratio (OR) of 1.26 (95% CI 1.23–1.28) compared to those with the highest income. History of cervical cancer and high parity were also associated with lower treatment rates. Conclusion: This study presents novel factors beyond the infection which seem to affect the antibiotic treatment for uncomplicated cystitis in women. Future studies to investigate possible mechanisms are warranted in order to properly use our findings. This may help healthcare workers and planners to provide a more equal treatment plan for this common infection, which may reduce misuse of antibiotics, decrease costs and improve efforts against antibiotic resistance.Filip JansåkerXinjun LiJenny Dahl KnudsenVeronica Milos NymbergKristina SundquistMDPI AGarticleantibioticscervical cancercystitisparitysociodemographic factorsUTITherapeutics. PharmacologyRM1-950ENAntibiotics, Vol 10, Iss 1389, p 1389 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	antibiotics cervical cancer cystitis parity sociodemographic factors UTI Therapeutics. Pharmacology RM1-950
spellingShingle	antibiotics cervical cancer cystitis parity sociodemographic factors UTI Therapeutics. Pharmacology RM1-950 Filip Jansåker Xinjun Li Jenny Dahl Knudsen Veronica Milos Nymberg Kristina Sundquist The Effect of Sociodemographic Factors, Parity and Cervical Cancer on Antibiotic Treatment for Uncomplicated Cystitis in Women: A Nationwide Cohort Study
description	Background: Uncomplicated cystitis is one of the most common reasons for antibiotic treatment in otherwise healthy women. Nationwide studies on antibiotic treatment for this infection and in relation to factors beyond the infection itself have hitherto not been available. Methods: This was a nationwide open cohort study consisting of 352,507 women aged 15–50 years with uncomplicated cystitis (2006–2018). The outcome was a redeemed antibiotic prescription within five days from the cystitis diagnosis. Logistic regression models were used to examine the relationship between the outcome and the predictor variables. Results: This study identified 192,065 redeemed treatments (54.5%). Several sociodemographic variables were associated with antibiotic treatment. For example, women with the lowest income had an odds ratio (OR) of 1.26 (95% CI 1.23–1.28) compared to those with the highest income. History of cervical cancer and high parity were also associated with lower treatment rates. Conclusion: This study presents novel factors beyond the infection which seem to affect the antibiotic treatment for uncomplicated cystitis in women. Future studies to investigate possible mechanisms are warranted in order to properly use our findings. This may help healthcare workers and planners to provide a more equal treatment plan for this common infection, which may reduce misuse of antibiotics, decrease costs and improve efforts against antibiotic resistance.
format	article
author	Filip Jansåker Xinjun Li Jenny Dahl Knudsen Veronica Milos Nymberg Kristina Sundquist
author_facet	Filip Jansåker Xinjun Li Jenny Dahl Knudsen Veronica Milos Nymberg Kristina Sundquist
author_sort	Filip Jansåker
title	The Effect of Sociodemographic Factors, Parity and Cervical Cancer on Antibiotic Treatment for Uncomplicated Cystitis in Women: A Nationwide Cohort Study
title_short	The Effect of Sociodemographic Factors, Parity and Cervical Cancer on Antibiotic Treatment for Uncomplicated Cystitis in Women: A Nationwide Cohort Study
title_full	The Effect of Sociodemographic Factors, Parity and Cervical Cancer on Antibiotic Treatment for Uncomplicated Cystitis in Women: A Nationwide Cohort Study
title_fullStr	The Effect of Sociodemographic Factors, Parity and Cervical Cancer on Antibiotic Treatment for Uncomplicated Cystitis in Women: A Nationwide Cohort Study
title_full_unstemmed	The Effect of Sociodemographic Factors, Parity and Cervical Cancer on Antibiotic Treatment for Uncomplicated Cystitis in Women: A Nationwide Cohort Study
title_sort	effect of sociodemographic factors, parity and cervical cancer on antibiotic treatment for uncomplicated cystitis in women: a nationwide cohort study
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/5f8268b3c9ac4b75b9a494109f4adbd7
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The Effect of Sociodemographic Factors, Parity and Cervical Cancer on Antibiotic Treatment for Uncomplicated Cystitis in Women: A Nationwide Cohort Study

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