Association between cognitive impairment and poor antihypertensive medication adherence in elderly hypertensive patients without dementia

Abstract Adherence to antihypertensive medication is a critical factor to control blood pressure and prevent complications. However, cognitive impairment can negatively affect medication adherence. In this study, we investigated the association between cognitive function and antihypertensive medicat...

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Autores principales:	Mi Hee Cho, Dong Wook Shin, Sung-A Chang, Ji Eun Lee, Su-Min Jeong, Sang Hyuck Kim, Jae Moon Yun, Kiyoung Son
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5f888d36a801411eacef9b54a3032950
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spelling	oai:doaj.org-article:5f888d36a801411eacef9b54a30329502021-12-02T15:08:54ZAssociation between cognitive impairment and poor antihypertensive medication adherence in elderly hypertensive patients without dementia10.1038/s41598-018-29974-72045-2322https://doaj.org/article/5f888d36a801411eacef9b54a30329502018-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-29974-7https://doaj.org/toc/2045-2322Abstract Adherence to antihypertensive medication is a critical factor to control blood pressure and prevent complications. However, cognitive impairment can negatively affect medication adherence. In this study, we investigated the association between cognitive function and antihypertensive medication adherence among elderly hypertensive patients using the Korean National Health Insurance Service National Sample Cohort Data of the Elderly Cohort. The study included 20,071 elderly hypertensive patients and the prevalence of poor medication adherence to antihypertensive medications was 16.4%. A multivariate logistic regression analysis showed that lower cognitive function was associated with poor medication adherence (adjusted odds ratio 0.980, 95% confidence interval 0.961–0.999). Additionally, high income levels, living in metropolitan areas, and comorbidities (such as stroke, coronary heart disease, diabetes, and dyslipidemia) were positively associated with medication adherence, while patients diagnosed with cancers showed poor medication adherence. Our study demonstrated that cognitive impairment is a possible risk factor for poor antihypertensive medication adherence, even in patients without dementia. Thus, clinicians involved with geriatric care should monitor patients’ cognitive function and medication adherence. And if a patient shows cognitive impairment, clinicians need to educate patients and caregivers about the importance of proper adherence, and consider proper interventions to optimize the cognitive function of elderly patients.Mi Hee ChoDong Wook ShinSung-A ChangJi Eun LeeSu-Min JeongSang Hyuck KimJae Moon YunKiyoung SonNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mi Hee Cho Dong Wook Shin Sung-A Chang Ji Eun Lee Su-Min Jeong Sang Hyuck Kim Jae Moon Yun Kiyoung Son Association between cognitive impairment and poor antihypertensive medication adherence in elderly hypertensive patients without dementia
description	Abstract Adherence to antihypertensive medication is a critical factor to control blood pressure and prevent complications. However, cognitive impairment can negatively affect medication adherence. In this study, we investigated the association between cognitive function and antihypertensive medication adherence among elderly hypertensive patients using the Korean National Health Insurance Service National Sample Cohort Data of the Elderly Cohort. The study included 20,071 elderly hypertensive patients and the prevalence of poor medication adherence to antihypertensive medications was 16.4%. A multivariate logistic regression analysis showed that lower cognitive function was associated with poor medication adherence (adjusted odds ratio 0.980, 95% confidence interval 0.961–0.999). Additionally, high income levels, living in metropolitan areas, and comorbidities (such as stroke, coronary heart disease, diabetes, and dyslipidemia) were positively associated with medication adherence, while patients diagnosed with cancers showed poor medication adherence. Our study demonstrated that cognitive impairment is a possible risk factor for poor antihypertensive medication adherence, even in patients without dementia. Thus, clinicians involved with geriatric care should monitor patients’ cognitive function and medication adherence. And if a patient shows cognitive impairment, clinicians need to educate patients and caregivers about the importance of proper adherence, and consider proper interventions to optimize the cognitive function of elderly patients.
format	article
author	Mi Hee Cho Dong Wook Shin Sung-A Chang Ji Eun Lee Su-Min Jeong Sang Hyuck Kim Jae Moon Yun Kiyoung Son
author_facet	Mi Hee Cho Dong Wook Shin Sung-A Chang Ji Eun Lee Su-Min Jeong Sang Hyuck Kim Jae Moon Yun Kiyoung Son
author_sort	Mi Hee Cho
title	Association between cognitive impairment and poor antihypertensive medication adherence in elderly hypertensive patients without dementia
title_short	Association between cognitive impairment and poor antihypertensive medication adherence in elderly hypertensive patients without dementia
title_full	Association between cognitive impairment and poor antihypertensive medication adherence in elderly hypertensive patients without dementia
title_fullStr	Association between cognitive impairment and poor antihypertensive medication adherence in elderly hypertensive patients without dementia
title_full_unstemmed	Association between cognitive impairment and poor antihypertensive medication adherence in elderly hypertensive patients without dementia
title_sort	association between cognitive impairment and poor antihypertensive medication adherence in elderly hypertensive patients without dementia
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/5f888d36a801411eacef9b54a3032950
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Association between cognitive impairment and poor antihypertensive medication adherence in elderly hypertensive patients without dementia

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